933724

Linear polyethylenimine-block-poly(ethylene glycol)

PEG average M_n 5,000, PEI average M_n 10,000

• 同義詞: PEG-PEI, PEG-b-PEI, Poly(ethylene glycol)-block-polyethylenimine
• 線性公式: CH₃(C₂H₄O)_n(C₂H₅N)_mOH
• 分類程式碼代碼: 12352207
• NACRES: NA.21

屬性

• 形狀: powder or solid
• 品質等級: 100
• 分子量: PEG M_n 5,000 Da; PEG average M_n 5,000; PEI M_n 10,000 Da; PEI average M_n 10,000
• 顏色: white to pale yellow
• 儲存溫度: 2-8°C

描述

應用

Due to their low immunogenicity profiles, polymeric nonviral vectors have shown promise in advancing the treatment of many severe genetic and acquired diseases via gene therapy. Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable