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931853

Sigma-Aldrich

SPhos Pd G6 acylation

greener alternative

≥95%

同義詞:

(SPhos)Pd(4-CH2CH2CONHSPh)Br

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About This Item

經驗公式(希爾表示法):
C39H47BrNO6PPd
CAS號碼:
分子量::
843.09
MDL號碼:
分類程式碼代碼:
12352100
NACRES:
NA.21

品質等級

化驗

≥95%

形狀

powder

反應適用性

reagent type: catalyst
reaction type: Cross Couplings

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Catalysis
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應用

SPhos Pd G6 acylation is an oxidative addition complex (OAC) of SPhos for use in bioconjugation. The pendant NHS-functional group allows coupling to protein amines through a selective acylation. The protein-OAC can then be reacted with a second, cysteine-containing protein. This facile approach allows for protein homodimerization as well as the formation of antibody-protein conjugates.

Learn more about G6 Buchwald precatalysts

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描述
訂價

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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文章

Buchwald G6 precatalysts are oxidative addition complexes that are thermally, air, and moisture stable. The catalyst activation doesn’t require a base and generates innocuous byproducts.

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