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Merck
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重要文件

930016

Sigma-Aldrich

TissueFab® bioink 

Facile Curable GelHA, Ionic

同義詞:

3D bioprinting, Bioink, Facile Curable, Gelatin, Hyaluronic Acid

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About This Item

分類程式碼代碼:
12352201
NACRES:
NA.25

品質等級

無菌

0.2 μm filtered

形狀

viscous liquid ((or gel))

雜質

<5 CFU/g Bioburden (Total Aerobic)
<5 CFU/g Bioburden (fungal)
<50 EU/mL Endotoxin

顏色

colorless to pale yellow

pH值

6.5-7.5

黏度

5-35 cP(37 °C)

應用

3D bioprinting

儲存溫度

2-8°C

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一般說明

Facile curable bioinks are ready-to-print bioinks formulated to crosslink without the necessity of light irradiation which can be detrimental to cell health. The bioink has a Gelatin base which as a natural protein offers excellent cytocompatibility and cell-binding motifs in order to mimic the native extracellular (ECM) microenvironment. The bioink can be crosslinked in a dilute solution of multivalent cations including TissueFab® - crosslinking solution (Cat#919926). TissueFab® - Facile curable HA bioink also contains hyaluronic acid (HA), a natural polysaccharide found ubiquitously throughout the body and cellular ECM. Cell can recognize HA through cell surface receptors CD44 and RHAMM and also degrade it through secretion of hyaluronidase.

Low bioburden: Bioburden is defined as the number of contaminated organisms found in a given amount of material. We test each lot for endotoxins as well as total bioburden (aerobic and fungal) to minimize unwanted interactions. For more information: https://www.sigmaaldrich.com/US/en/technical-documents/technical-article/microbiological-testing/pyrogen-testing/what-is-endotoxin

法律資訊

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3


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分析證明 (COA)

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Kevin T Dicker et al.
Acta biomaterialia, 10(4), 1558-1570 (2013-12-24)
Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell surface and even inside cells. Being a simple polysaccharide, HA exhibits

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