推薦產品
反應適用性
reagent type: linker
品質等級
官能基
Boc
carboxylic acid
SMILES 字串
CC(C)(OC(N1CCCC(N2C=C(C=N2)CC(O)=O)C1)=O)C
應用
2-(1-(1-(tert-Butoxycarbonyl)piperidin-3-yl)-1H-pyrazol-4-yl)acetic acid is useful as a rigid linker in PROTAC development for targeted protein degradation as well as chemical conjugates. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties. Developed in partnership with ComInnex.
Similar linkers in this series:
920533
920649
920673
920703
Similar linkers in this series:
920533
920649
920673
920703
其他說明
法律資訊
PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license
Practum is a registered trademark of Sartorius Lab Instruments GmbH & Co. KG
相關產品
產品號碼
描述
訂價
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務