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Merck
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Key Documents

911496

Sigma-Aldrich

Polyester bis-MPA dendron, 4 carboxyl, 1 Rhodamine (core)

generation 2

同義詞:

Bis-MPA dendron, Fluorescent linker, Fluoresent dendron

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About This Item

經驗公式(希爾表示法):
C67H87ClN2O28
分子量::
1403.86
分類程式碼代碼:
12162002
NACRES:
NA.23

一般說明

  • Polymer architecture: Dendron
  • End Group Functionality: Carboxyl
  • Bis-MPA: 2,2-Bis(hydroxymethyl)propionic acid

應用

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allow their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers is biocompatible and biodegradable, making them suitable for biomedical applications.
The corona of this product is functionalized by carboxyl groups, which can be readily used in bioconjugation. The rhodamine labeled core allows its application in bioimaging.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Patrik Stenström et al.
Molecules (Basel, Switzerland), 23(8) (2018-08-17)
Herein, we present the first evaluation of cationic dendrimers based on 2,2-bis(methylol)propionic acid (bis-MPA) as nonviral vectors for transfection of short interfering RNA (siRNA) in cell cultures. The study encompassed dendrimers of generation one to four (G1⁻G4), modified to bear
Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications.
Garcia-Gallego S, et al
Progress in Polymer Science, 48, 85-110 (2015)
Anna Carlmark et al.
Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

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