907197

1,4-Dinitro-1-imidazole

• 同義詞: 1,4-DNIm, 1,4-Dinitroimidazole, Bifunctional bioconjugation reagent
• 經驗公式（希爾表示法）: C₃H₂N₄O₄
• CAS號碼: 19182-81-1
• 分子量：: 158.07
• MDL號碼: MFCD00297235
• 分類程式碼代碼: 12352005

屬性

• 化驗: ≥95%
• 形狀: solid
• 儲存溫度: −20°C
• InChI: 1S/C3H2N4O4/c8-6(9)3-1-5(2-4-3)7(10)11/h1-2H
• InChI 密鑰: HZPSREFSUPXCMN-UHFFFAOYSA-N

描述

應用

1,4-Dinitro-1-imidazole (1,4-DNIm) and other dinitroimidazoles were demonstrated to be bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization. In acidic to neutral aqueous conditions, 1,4-DNIms chemoselectively react with cysteines; in organic solvents in the presence of base, 1,4-DNIms chemoselectively react with lysines to form stable conjugates

其他說明

Dinitroimidazoles as bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302
• 防範說明: P264 - P270 - P301 + P312 - P501
• 危險分類: Acute Tox. 4 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable