901841

N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(ε-caprolactone)

PEG average M_n 5,000, PCL average M_n 5,000

• 同義詞: NHS ester PEG-PCL diblock copolymer, NHS ester-PEG-PCL, PEG-b-PCL, PEG-PCL
• 線性公式: C₁₀H₁₄NO₅S[C₂H₄O]_n[C₆H₁₀O₂]_mH
• 分類程式碼代碼: 12352005
• NACRES: NA.23

屬性

• 形狀: powder or solid
• 分子量: PCL average M_n 5,000; PEG average M_n 5,000
• 顏色: white to off-white
• 蛋白質二硫鍵異構酶: ≤1.3 (by GPC)
• 儲存溫度: −20°C

描述

應用

N-Hydroxysuccinimide ester-poly(ethylene glycol)-b-poly(ε-caprolactone) is a functionalized, amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PCL block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics). Additionally, well-defined nanoparticles with tunable size and properties can be prepared by altering the molecular weight ratios between hydrophilic and hydrophobic blocks, as well as by controlling formulation parameters. The NHS ester functional group on the PEG chain enables rapid and facile surface functionalization, allowing for these materials to be used in applications such as targeted drug delivery.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable