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Merck
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重要文件

86971

Sigma-Aldrich

Fmoc-Dab(Boc)-OH

≥97.0% (HPLC)

同義詞:

Nα-芴甲氧羰基-Nγ-叔丁氧羰基-L-2,4-二氨基丁酸

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About This Item

經驗公式(希爾表示法):
C24H28N2O6
CAS號碼:
分子量::
440.49
Beilstein:
6250328
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26

品質等級

化驗

≥97.0% (HPLC)

形狀

powder

光學活性

[α]20/546 −14.5±1°, c = 1% in methanol

反應適用性

reaction type: Fmoc solid-phase peptide synthesis

應用

peptide synthesis

官能基

Boc
Fmoc

儲存溫度

2-8°C

SMILES 字串

CC(C)(C)OC(=O)NCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O

InChI

1S/C24H28N2O6/c1-24(2,3)32-22(29)25-13-12-20(21(27)28)26-23(30)31-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,26,30)(H,27,28)/t20-/m0/s1

InChI 密鑰

LIWKOFAHRLBNMG-FQEVSTJZSA-N

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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Taking a minimalistic approach in efforts to lower the cost for the development of new synthetic antimicrobial peptides, ultrashort cationic lipopeptides were designed to mimic the amphiphilic nature crucial for their activity but with only a very short peptide sequence
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European journal of medicinal chemistry, 136, 154-164 (2017-05-12)
The 20-residue linear peptide A20FMDV2 has been shown to exhibit high selectivity and affinity for the tumour-related αvβ6 integrin and has potential as a vector for therapeutic drugs. However, it exhibits poor half-life in plasma in part due to its
Tony Velkov et al.
Cell chemical biology, 25(4), 380-391 (2018-02-06)
Resistance to the last-resort antibiotic colistin is now widespread and new therapeutics are urgently required. We report the first in toto chemical synthesis and pre-clinical evaluation of octapeptins, a class of lipopeptides structurally related to colistin. The octapeptin biosynthetic cluster consisted

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