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81300

Sigma-Aldrich

聚（乙二醇）

average MN 20,000, hydroxyl

同義詞:

PEG

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About This Item

線性公式:
H(OCH2CH2)nOH
CAS號碼:
25322-68-3
MDL號碼:
MFCD00081839
分類程式碼代碼:
12352104
PubChem物質ID:
24887748
NACRES:
NA.23

產品名稱

聚（乙二醇）, average Mn 20,000

形狀

flakes

分子量

average Mn 20,000

mp

63-66 °C

Ω-end

hydroxyl

α-end

hydroxyl

SMILES 字串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI 密鑰

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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相關類別

一般說明

聚乙二醇（PEG）是亲水性聚合物。它可以通过环氧乙烷的阴离子开环聚合很容易地合成，得到一系列分子量和各种端基。当交联成网时，PEG可具有很高的含水量，形成“水凝胶”。可以通过电离辐射使PEG交联或通过PEG大分子单体与反应性链端共价交联来引发水凝胶形成。PEG是适合生物学应用的材料，因为它不会引发免疫反应。

應用

PEG被用于修饰治疗性蛋白和肽，以增加溶解度、降低毒性。

光聚合的PEG水凝胶在制备生物活性和免疫隔离的屏障用于细胞包封方面具有新兴应用。

其他說明

分子量：Mn为16,000-24,000

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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分析證明 (COA)

Lot/Batch Number
BCCG4865
BCCG4864
BCCF7279
BCCF7277
BCCD8215

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Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Versatile Cell Culture Scaffolds via Bio-orthogonal Click Reactions

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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