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765589

Sigma-Aldrich

官能化金纳米粒子COOH

50 nm diameter, carboxylic acid functionalized, PEG 5000 coated, dispersion in H2O

同義詞:

Au NP COOH, 金胶体

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About This Item

分類程式碼代碼:
12162002
NACRES:
NA.23

材料

PEG 5000

品質等級

100

形狀

dispersion in H2O
nanoparticles

包裝

poly bottle of 1 mL

外徑

50

直徑

50 nm

pH值

6.0-8.0 (25 °C)

溶解度

water: miscible

密度

1.00 g/cm3

λmax

535 nm

官能基

carboxylic acid

儲存溫度

2-8°C

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相關類別

一般說明

Carboxylic acid functionalized GNPs forms conjugates with various protein molecules due to the electrostatic attraction between negatively charged carboxylate groups and positively charged amino groups of protein.

應用

Gold nanoparticles 50 nm diameter, carboxylic acid functionalized, PEG 5000 coated, dispersion in H2O can be potentially used in the development of biosensors, cancer-cell imaging, drug delivery, and photothermal therapy.
AuNPs may also be used in the immobilization of antibodies to improve the sensitivity of optical fiber sensors for the screening of COVID-19. It can also be deposited on the titanium electrode for the formation of a miniaturized device for the electrochemical detection of DNA hybridization.
The carboxylic acid group binds with proteins and is used in targeted drug delivery and gene therapy.
功能化颗粒已被广泛用于研究纳米颗粒的细胞摄取和靶向药物递送。

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number
MKCN0239
MKCB6011
MKBN9292V
MKBL7647V

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Functionalized gold nanoparticles and their biomedical applications
Nanomaterials, 1(1), 31-63 (2011)
Optical Fiber Sensors for Rapid Screening of COVID-19
Nag P, et al.
Transactions of the Indian National Academy of Engineering, 6, 1-4 (2020)
Size-dependent in vivo toxicity of PEG-coated gold nanoparticles
Zhang X, et al.
International journal of nanomedicine, 6, 2071-2071 (2011)
Nishima Wangoo et al.
Journal of colloid and interface science, 323(2), 247-254 (2008-05-20)
We report a novel strategy for the synthesis of aqueous stable, carboxylated gold nanoparticles (GNPs) by using glutamic acid as the reducing agent. The ratio of chloroaurate ions, AuCl(-)(4) to glutamic acid was optimized in the reaction medium to obtain

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