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Sigma-Aldrich

N-羟基琥珀酰亚胺 (NHS) 酯封端的聚(N-异丙基丙烯酰胺)

average Mn 2,000

同義詞:

NIPAM 聚合物, PNIPAM-NHS, 功能化聚(N-异丙基丙烯酰胺), 功能化聚丙烯酰胺, 聚(N-异丙基丙烯酰胺), 聚丙烯酰胺

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About This Item

線性公式:
(C6H11NO)n SCH2CH2COO(C4H4NO2)
分類程式碼代碼:
12162002
NACRES:
NA.23

形狀

powder

品質等級

100

分子量

average Mn 2,000

mp

>300 °C

相關類別

應用

细胞膜片组织工程用PNIPAM类智能表面
用于开发热敏涂层微/纳米材料的新型聚合物，包括热响应性聚合物药物递送系统。 NHS酯官能团可用于使多种生物分子（如酶）与聚合物链偶联。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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Sigma-Aldrich

JKA5021

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A four-arm star block copolymer, comprised of a hydrophobic PMMA arm and an average of three hydrophilic poly(N-isopropylacrylamide) (PNIPAAm) arms were designed and synthesized from the molecular level. The amphiphilic star block copolymer is capable of self-assembling into micelles in
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We report a novel drug delivery system for apoptosis induction by a "smart" polymer vehicle possessing thermosensitivity and bioaffinity. The polymer chain was prepared by copolymerization of N-isopropylacrylamide and N-methacryloyloxysuccinimide. Cell-adhesive RGDS peptide was conjugated with the copolymer as a

文章

Designing temperature and pH sensitive NIPAM based polymers

Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.

Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering

Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.

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By altering the physicochemical properties, smart or intelligent drug delivery systems can be designed to deliver therapeutic molecules on-demand. Learn more about the application of stimuli-responsive materials in drug delivery.

Functional Polymers for Biomedical Applications

Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "

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