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重要文件

662534

Sigma-Aldrich

4-巯基苯甲酸

technical grade, 90%

同義詞:

4-巯基苯甲酸, 对巯基苯甲酸

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About This Item

線性公式:
HSC6H4CO2H
CAS號碼:
分子量::
154.19
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

等級

technical grade

品質等級

化驗

90%

形狀

solid

mp

215-224 °C (lit.)

官能基

carboxylic acid

SMILES 字串

OC(=O)c1ccc(S)cc1

InChI

1S/C7H6O2S/c8-7(9)5-1-3-6(10)4-2-5/h1-4,10H,(H,8,9)

InChI 密鑰

LMJXSOYPAOSIPZ-UHFFFAOYSA-N

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一般說明

4-巯基苯甲酸 (4-MBA)又称 4-羧硫酚或对巯基苯甲酸,是一种用于有机合成的芳香族化合物。 4-MBA 通过其活性硫醇 (-SH) 基团促进二硫键的形成。硫醇基团中的硫原子 具有高度亲核性,能够攻击亲电试剂。 促进各种含硫醇化合物的形成。 此外,4-MBA 可作为配体形成配位复合物,并用于表面官能化——特别是在金属表面创建自组装单层 (SAM)。

應用

  • 食品掺假检测的SERS底物:采用4-巯基苯甲酸通过生物聚合物层层组装,原位制造AuNP等离子体纸,可作为表面增强拉曼散射(SERS)基底用于食品掺假检测(Viriyakitpattana et al., 2024)。
  • 磁性-等离子体纳米粒子的开发:结合激光烧蚀和溶剂热法获得磁性-等离子体纳米粒子,可用于4-巯基苯甲酸为标记分子的多波长SERS。说明纳米颗粒合成的多样性(Talaikis et al., 2023)。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Molly K Gregas et al.
Applied spectroscopy, 64(8), 858-866 (2010-08-20)
We describe the development and application of a co-functionalized nanoprobe and biodelivery platform combining a nuclear targeting peptide (NTP) for improved cellular uptake and intracellular targeting with p-mercaptobenzoic acid (pMBA) as a surface-enhanced Raman scattering (SERS) reporter for tracking and
Wen-Tsen Chen et al.
Journal of the American Society for Mass Spectrometry, 21(5), 864-867 (2010-02-23)
We have developed a new internal standard method for the determination of the concentration of captopril (CAP) through surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) using gold nanoparticles (Au NPs). This approach provided linearity for CAP over the concentration range 2.5-25
Aleksandra Jaworska et al.
The Analyst, 140(7), 2321-2329 (2014-12-09)
The intracellular pH plays an important role in various cellular processes. In this work, we describe a method for monitoring of the intracellular pH in endothelial cells by using surface enhanced Raman spectroscopy (SERS) and 4-mercaptobenzoic acid (MBA) anchored to
Fenglin Wang et al.
Analytical chemistry, 84(18), 8013-8019 (2012-08-14)
Sensors based upon surface-enhanced Raman spectroscopy (SERS) are attractive because they have narrow, vibrationally specific spectral peaks that can be excited using red and near-infrared light which avoids photobleaching, penetrates tissue, and reduces autofluorescence. Several groups have fabricated pH nanosensors
Garima Gupta et al.
Biosensors & bioelectronics, 36(1), 95-102 (2012-04-27)
Surface plasmon resonance (SPR) immunosensor using 4-mercaptobenzoic acid (4-MBA) modified gold SPR chip was developed first time for the detection of flagellin specific antibodies of Salmonella typhi (S. typhi). Flagellin protein of S. typhi was prepared by recombinant DNA technology.

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