推薦產品
化驗
97%
形狀
solid
mp
310 °C (lit.)
官能基
carboxylic acid
SMILES 字串
OC(=O)c1ccc(OCCCOc2ccc(cc2)C(O)=O)cc1
InChI
1S/C17H16O6/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H,18,19)(H,20,21)
InChI 密鑰
VBISQLWPGDULSX-UHFFFAOYSA-N
應用
用于聚酐（一类应用于多种给药系统的生物可蚀性聚合物）的结构单元。
訊號詞
Warning
危險聲明
危險分類
Aquatic Acute 1 - Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
A J Domb et al.
Biomaterials, 15(9), 681-688 (1994-07-01)
The metabolic disposition and elimination process of the anhydride co-polymer poly[1,3-bis(p-carboxy-phenoxypropane):sebacic acid] 20:80 [P(CPP:Sa)20:80] implanted in the rat brain was studied. Two polymers were prepared, one with [14C]SA and unlabelled CPP, and the other co-polymer with [14C]CPP and unlabelled SA.
Xiaohua Liu et al.
Biomaterials, 28(28), 4124-4131 (2007-06-20)
Intermittent (pulsatile) administration of parathyroid hormone (PTH) is known to improve bone micro-architecture, mineral density and strength. Therefore, daily injection of PTH has been clinically used for the treatment of osteoporosis. However, this regimen of administration is not convenient and
Moon Suk Kim et al.
Bio-medical materials and engineering, 15(3), 229-238 (2005-05-25)
p-Carboxyphenoxy propane (CPP) prepolymer consisting of 4 units and sebacic acid (SA) prepolymer consisting of about 10 units were synthesized by reacting CPP and SA in the presence of excess acetic anhydride, respectively. Polyanhydride, poly(CPP-SA) copolymers were copolymerized by a
A D'Emanuele et al.
Pharmaceutical research, 9(10), 1279-1283 (1992-10-01)
We report a study of the effects of polymer molecular weight on the erosion of polyanhydride copolymer matrices composed of 1,3-bis(p-carboxyphenoxy)-propane (CPP) and sebacic acid (SA) in aqueous solution. The erosion profile characteristically displays an induction period during which the
Sijian Hou et al.
Macromolecular bioscience, 7(5), 620-628 (2007-04-26)
To tailor the erosion rate of polyanhydrides while retaining their surface erosion characteristics, new three-component polyanhydrides of sebacic acid, 1,3-bis(p-carboxyphenoxy)propane and poly(ethylene glycol) were synthesized. The hydrophilicity of the polymer increased and its mechanical strength decreased with increasing PEG content.
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