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Merck
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重要文件

64430

Sigma-Aldrich

DL-蛋氨酸亚砜

≥98.5% (NT)

同義詞:

dl-Methionine sulfoxide

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About This Item

線性公式:
CH3SOCH2CH2CH(NH2)COOH
CAS號碼:
分子量::
165.21
Beilstein:
1723793
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥98.5% (NT)

反應適用性

reaction type: solution phase peptide synthesis

mp

~240 °C (dec.)

應用

peptide synthesis

SMILES 字串

CS(=O)CCC(N)C(O)=O

InChI

1S/C5H11NO3S/c1-10(9)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)

InChI 密鑰

QEFRNWWLZKMPFJ-UHFFFAOYSA-N

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一般說明

DL-蛋氨酸亚砜是DL-蛋氨酸的氧化产物。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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Christopher C Saunders et al.
Analytical biochemistry, 421(2), 767-769 (2012-01-11)
Study of the posttranslational modification of methionine to its sulfoxide has been receiving increasing attention because of its implication in regulation of protein activity, but techniques for the detection of this modification remain limited. In particular, there has been no
Noelle Callizot et al.
Journal of neuroscience research, 91(5), 706-716 (2013-02-14)
Alzheimer disease (AD) affects mainly people over the age of 65 years, suffering from different clinical symptoms such as progressive decline in memory, thinking, language, and learning capacity. The toxic role of β-amyloid peptide (Aβ) has now shifted from insoluble
Fiona M Sansom et al.
PloS one, 8(2), e56064-e56064 (2013-02-26)
Leishmania are protozoan parasites that proliferate within the phagolysome of mammalian macrophages. While a number of anti-oxidant systems in these parasites have been shown to protect against endogenous as well as host-generated reactive oxygen species, the potential role of enzymes
Edward Pelle et al.
Journal of cosmetic science, 63(6), 359-364 (2013-01-05)
Environmental trauma to human skin can lead to oxidative damage of proteins and affect their activity and structure. When methionine becomes oxidized to its sulfoxide form, methionine sulfoxide reductase A (MSRA) reduces it back to methionine. We report here the
Jesse J Robinet et al.
The journal of physical chemistry. B, 115(29), 9202-9212 (2011-07-05)
The hybrid density functional theory method B3LYP in combination with three systematically larger active site models has been used to investigate the substrate binding and catalytic mechanism by which Neisseria gonorrhoeae methionine sulfoxide reductase B (MsrB) reduces methionine-R-sulfoxide (Met-R-SO) to

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