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Merck
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重要文件

641472

Sigma-Aldrich

1-Boc-4-(氨基甲基)哌啶

97%

同義詞:

1,1-Dimethylethyl 4-(aminomethyl)-1-piperidinecarboxylate, N-(tert-Butoxycarbonyl)-4-aminomethylpiperidine

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About This Item

經驗公式(希爾表示法):
C11H22N2O2
CAS號碼:
分子量::
214.30
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

97%

折射率

n20/D 1.473 (lit.)

bp

237-238 °C (lit.)

密度

1.013 g/mL at 25 °C (lit.)

官能基

amine

SMILES 字串

CC(C)(C)OC(=O)N1CCC(CN)CC1

InChI

1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-9(8-12)5-7-13/h9H,4-8,12H2,1-3H3

InChI 密鑰

KLKBCNDBOVRQIJ-UHFFFAOYSA-N

應用

Precursor in the preparation of a variety of different protein agonists or antagonists including:
  • Kinesin spindle protein inhibitors with potential anticancer activity
  • Orphan G-protein coupled receptor GPR119 agonist with antidiabetic potential
  • Pim-1 inhibitors
  • Aspartic acid protease inhibitors

Reactant involved in enantioselective synthesis of N-alkyl terminal aziridines

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

No data available

閃點(°C)

No data available

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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文章

MRT - Mono-Boc-Protection of Diamines

Mono-Boc-protected diamines are versatile building blocks for chemical synthesis. Their production is a lot more challenging than the simple reaction scheme might imply, because the Boc-anhydride reagent cannot differentiate between the two identical amino moieties in the substrate.

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