推薦產品
品質等級
化驗
97%
形狀
solid
mp
58-62 °C
官能基
chloro
SMILES 字串
Cc1ccc(Cl)nn1
InChI
1S/C5H5ClN2/c1-4-2-3-5(6)8-7-4/h2-3H,1H3
InChI 密鑰
PRORLQAJNJMGAR-UHFFFAOYSA-N
應用
3-Chloro-6-methyl pyridazine can undergo nickel catalyzed cross coupling reaction with aromatic and heteroaromatic halides, to give the corresponding substituted aryl- and heteroaryl pyridazines. It can also be used in the synthesis of a p38MAP kinase inhibitor with therapeutic potential in the treatment of autoimmune and inflammatory diseases.
訊號詞
Danger
危險分類
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
"Development of a Practical and Scalable Synthesis of a Potent p38 Mitogen-Activated Protein Kinase Inhibitor"
The Journal of Organic Chemistry, 16(11), 1818-1826 (2012)
The Journal of Organic Chemistry, 72(15), 5631-5636 (2007)
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