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608033

Sigma-Aldrich

L-精氨酸-13C6,15N4 盐酸盐

99 atom % 13C, 99 atom % 15N, 95% (CP)

同義詞:

SILAC氨基酸, (S)-(+)-2-氨基-5-[(氨基甲基)氨基]戊酸-13C6,15N4盐酸盐, 13C和15标记的精氨酸, 13C和15标记的精氨酸盐酸盐

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About This Item

線性公式:
H215N13C(15NH)15NH(13CH2)313CH(15NH2)13CO2H · HCl
CAS號碼:
202468-25-5
分子量：:
220.59
MDL號碼:
MFCD04118221
分類程式碼代碼:
12352209
PubChem物質ID:
329759227
NACRES:
NA.12

同位素純度

99 atom % 13C
99 atom % 15N

品質等級

200

化驗

95% (CP)

形狀

solid

光學活性

[α]20/D +22°, c = 12 in 10% HCl

成份

L-isomer, 97%

技術

bio NMR: suitable
protein expression: suitable

mp

226-230 °C (dec.) (lit.)

質量偏移

M+10

儲存溫度

room temp

SMILES 字串

Cl.[15NH2][13C@@H]([13CH2][13CH2][13CH2][15NH][13C]([15NH2])=[15NH])[13C](O)=O

InChI

1S/C6H14N4O2.ClH/c7-4(5(11)12)2-1-3-10-6(8)9;/h4H,1-3,7H2,(H,11,12)(H4,8,9,10);1H/t4-;/m0./s1/i1+1,2+1,3+1,4+1,5+1,6+1,7+1,8+1,9+1,10+1;

InChI 密鑰

KWTQSFXGGICVPE-YAUSPDTOSA-N

相關類別

應用

脉冲稳定同位素标记氨基酸已用于研究HIV-1感染人单核细胞来源巨噬细胞的宿主细胞功能、存活和准确的胞内蛋白合成途径。

包裝

该产品有大量储备，可按需包装。 有关定价、供货和包装的信息，请联系稳定同位素客户服务。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

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分析證明 (COA)

Lot/Batch Number
MBBD2791
MBBC5181
MBBC4710
MBBC4371
MBBC3108

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Alex A Makarov et al.
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Science advances, 6(15), eaax2746-eaax2746 (2020-04-15)
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Heat shock protein-70 (HSP70) is crucial for proteostasis and displays cell-protective effects. Meanwhile, enhanced levels of cell-surface (cs) and secreted HSP70 paradoxically associate with pathologic cardiovascular conditions. However, mechanisms regulating csHSP70 pool are unknown. We hypothesized that total and csHSP70
Stephanie D Kraft-Terry et al.
Journal of proteome research, 10(6), 2852-2862 (2011-04-20)
Dynamic interactions between human immunodeficiency virus-1 (HIV-1) and the macrophage govern the tempo of viral dissemination and replication in its human host. HIV-1 affects macrophage phenotype, and the macrophage, in turn, can modulate the viral life cycle. While these processes
Arash Latifkar et al.
Developmental cell, 49(3), 393-408 (2019-04-16)
The NAD+-dependent deacetylase Sirtuin 1 (SIRT1) is down-regulated in triple-negative breast cancer. To determine the mechanistic basis by which reduced SIRT1 expression influences processes related to certain aggressive cancers, we examined the consequences of depleting breast cancer cells of SIRT1.
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相關內容

Protein Structural Analysis

Protein structure provides valuable information that can be used to infer protein function. The study of protein structure and mapping of protein interactions, expression levels, and location enables the identification of disease biomarkers and potential drug targets for therapeutic treatment.

Protein Structural Analysis

Protein structure analysis aids in identifying disease biomarkers and drug targets crucial for therapeutic treatments.

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