531316

N-(叔丁氧基羰基)-2-溴苯胺

97%

• 線性公式: BrC₆H₄HNCO₂C(CH₃)₃
• CAS號碼: 78839-75-5
• 分子量：: 272.14
• MDL號碼: MFCD01006614
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24877811
• NACRES: NA.22

屬性

• 品質等級: 100
• 化驗: 97%
• 折射率: n20/D 1.54 (lit.)
• bp: 110 °C/0.3 mmHg (lit.)
• 密度: 1.342 g/mL at 25 °C (lit.)
• 官能基: amine; bromo
• SMILES 字串: CC(C)(C)OC(=O)Nc1ccccc1Br
• InChI: 1S/C11H14BrNO2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8(9)12/h4-7H,1-3H3,(H,13,14)
• InChI 密鑰: UQBGKDLSIIHUEZ-UHFFFAOYSA-N

描述

一般說明

N-(tert-Butoxycarbonyl)-2-bromoaniline, also known as tert-butyl-N-(2-bromophenyl)carbamate, is an N-Boc-protected o-bromoaniline.1 It reacts with ethyl perfluorooctanoate in the presence of tert-butyllithium to form the corresponding 1-hydroxy-1H-perfluorooctyl compound.

應用

N-(tert-Butoxycarbonyl)-2-bromoaniline may be used in the synthesis of N-boc-protected o-aryl anilines, which undergoes coupling reaction with bromoacetylenes to form the corresponding arene?ynamides.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 230.0 °F - closed cup
• 閃點（°C）: 110 °C - closed cup
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves