466964

4'-氟-2'-羟基苯乙酮

98%

• 線性公式: FC₆H₃(OH)COCH₃
• CAS號碼: 1481-27-2
• 分子量：: 154.14
• MDL號碼: MFCD00143203
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24870373
• NACRES: NA.22

屬性

• 化驗: 98%
• mp: 31-35 °C (lit.)
• SMILES 字串: CC(=O)c1ccc(F)cc1O
• InChI: 1S/C8H7FO2/c1-5(10)7-3-2-6(9)4-8(7)11/h2-4,11H,1H3
• InChI 密鑰: HLTBTUXAMVOKIH-UHFFFAOYSA-N

描述

一般說明

4′-Fluoro-2′-hydroxyacetophenone is a substituted acetophenone derivative. Biological Baeyer-Villiger oxidation of 4′-fluoro-2′-hydroxyacetophenone to 4-fluorocatechol by using whole cells of Pseudomonas fluorescens ACB has been reported. Its crystals belong to the monoclinic crystal system and space group P2₁/n.

應用

最近用于制备具有药用活性的苯并[b]呋喃类化合物和噻吩类化合物。

4′-Fluoro-2′-hydroxyacetophenone may be used in the preparation of series of 4′-fluoro-2′-hydroxychalcones, via aldol condensation with substituted aldehydes followed by cyclization with hydrazine hydrate.

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 210.2 °F - closed cup
• 閃點（°C）: 99 °C - closed cup
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves