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341894

Sigma-Aldrich

溴化氰 溶液

3.0 M in methylene chloride

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About This Item

線性公式:
BrCN
CAS號碼:
分子量::
105.92
Beilstein:
1697296
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

形狀

liquid

濃度

3.0 M in methylene chloride

溶解度

alcohol: freely soluble
diethyl ether: freely soluble
water: freely soluble

密度

1.443 g/mL at 25 °C

官能基

bromo

SMILES 字串

BrC#N

InChI

1S/CBrN/c2-1-3

InChI 密鑰

ATDGTVJJHBUTRL-UHFFFAOYSA-N

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一般說明

溴化氰溶液仅在N-取代吗啉存在下诱导模板引导的寡核苷酸缩合。研究了N-取代吗啉缓冲液中溴化氰激活磷酸单酯基团的机理。

應用

溴化氰(CNBr)溶液可用于溴化氰法将胰蛋白酶共价固定在聚(2-羟乙基甲基丙烯酸酯)/聚苯乙烯复合微球上。它可用于制备CNBr活化的二醇二氧化硅,可用作HPLC中的二氧化硅载体。

訊號詞

Danger

危險分類

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Carc. 2 - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

標靶器官

Central nervous system

安全危害

儲存類別代碼

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Luis A Jurado et al.
Journal of chromatography. A, 971(1-2), 95-104 (2002-09-28)
To obtain silica supports for high-performance affinity chromatography, a method of preparing CNBr-activated diol-silica under anhydrous conditions was developed. Activation of the silane-derived hydroxyls with cyanogen bromide and triethylamine was optimized and demonstrated to efficiently couple several amino ligands (tryptophan
Z A Shabarova et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 27(5-6), 555-566 (2001-09-07)
Cyanogen bromide has been found to induce the template-guided condensation of oligonucleotides only in the presence of N-substituted morpholines. Based on 31P, 1H and 13C NMR spectroscopy data, the mechanism of the phosphomonoester group activation by cyanogen bromide in N-substituted
Covalent immobilization of trypsin onto poly (2-hydroxyethyl methacrylate)/polystyrene composite microspheres by cyanogen bromide method and its enzymatic activity.
Okubo M, et al.
Colloid and Polymer Science, 265(11), 957-964 (1987)
Bart Vanelslander et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(7), 2412-2417 (2012-02-07)
The spatial organization of biofilms is strongly regulated by chemical cues released by settling organisms. However, the exact nature of these interactions and the repertoire of chemical cues and signals that micro-organisms produce and exude in response to the presence
Deborah Negrão-Corrêa et al.
PloS one, 9(2), e88042-e88042 (2014-02-08)
Studies in murine models and human populations have indicated that the collagen-rich granulomatous response against parasite eggs trapped in the liver is associated with the development of severe hepatosplenic schistosomiasis, characterized by periportal fibrosis and portal hypertension. The role of

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