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Merck
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重要文件

309346

Sigma-Aldrich

L-谷氨酸二乙酯 盐酸盐

97%

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About This Item

線性公式:
C2H5OCOCH2CH2CH(NH2)COOC2H5 · HCl
CAS號碼:
分子量::
239.70
Beilstein:
3597595
EC號碼:
MDL號碼:
分類程式碼代碼:
12352209
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

97%

光學活性

[α]18/D +22°, c = 1 in H2O

反應適用性

reaction type: solution phase peptide synthesis

mp

108-110 °C (lit.)

應用

peptide synthesis

SMILES 字串

Cl[H].CCOC(=O)CC[C@H](N)C(=O)OCC

InChI

1S/C9H17NO4.ClH/c1-3-13-8(11)6-5-7(10)9(12)14-4-2;/h7H,3-6,10H2,1-2H3;1H/t7-;/m0./s1

InChI 密鑰

WSEQLMQNPBNMSL-FJXQXJEOSA-N

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應用

L-Glutamic acid diethyl ester hydrochloride can be used in the synthesis of:
  • Oligo(γ-ethyl L-glutamate) via oligomerization catalyzed by papain.
  • L-glutamic acid based dendritic compounds.
  • Poly(α-peptide) by polymerization and copolymerization in the presence of protease catalysts.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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分析證明 (COA)

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Rapid regioselective oligomerization of L-glutamic acid diethyl ester catalyzed by papain
Li G, et al.
Macromolecules, 39(23), 7915-7921 (2006)
Ultrasound induced formation of organogel from a glutamic dendron
Li Y, et al.
Tetrahedron, 63(31), 7468-7473 (2007)
Inhibition of cocaine intoxication by excitatory amino acid receptor antagonists.
R W Rockhold et al.
Annals of the New York Academy of Sciences, 648, 335-337 (1992-05-11)
Manoel Jorge Nobre et al.
Life sciences, 71(25), 2961-2972 (2002-10-18)
Gradual increases in the electrical stimulation of the inferior colliculus produces progressive aversive responses from vigilance, through freezing, until escape. These responses are probably mediated by excitatory amino acids (EAA) mechanisms as microinjection of glutamate into the inferior colliculus can
T Kubo et al.
Brain research, 616(1-2), 311-314 (1993-07-09)
Neonatal Wistar rats were subcutaneously injected with 0.1, 1, or 2 mg/g b.wt. of monosodium glutamate (MSG) at 1, 3, 5, 7, and 9 days after birth. The animals were observed for degeneration of pyramidal cells in the hippocampus. The

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