推薦產品
化驗
97%
形狀
solid
mp
80-83 °C (lit.)
SMILES 字串
C1COCCN(CCOCCOCCN(CCO1)Cc2ccccc2)Cc3ccccc3
InChI
1S/C26H38N2O4/c1-3-7-25(8-4-1)23-27-11-15-29-19-21-31-17-13-28(24-26-9-5-2-6-10-26)14-18-32-22-20-30-16-12-27/h1-10H,11-24H2
InChI 密鑰
WAHZGOBRKWVALN-UHFFFAOYSA-N
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應用
7,16-Dibenzyl-1,4,10,13-tetraoxa-7,16-diazacyclooctadecane can be used:
- As a macrocycle that facilitates the modification of the electrode used in the estimation of riboflavin or vitamin B2 in food and pharmaceutical samples.
- As an ionophore in the preparation of poly(vinyl chloride) membrane-based Zn2+ sensor applicable in the estimation of Zn in water and drug samples.
- To prepare a modified graphite electrode, which is used in the detection of samarium in ores and industrial effluents.
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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18-crown-6 ethers are known to exert their biological activity by transporting K(+) ions across cell membranes. Using non-linear Support Vector Machines regression, we searched for structural features that influence antiproliferative activity in a diverse set of 19 known oxa-, monoaza-
Journal of medicinal chemistry, 50(5), 1007-1018 (2007-02-16)
The present paper demonstrates the antiproliferative ability and structure-activity relationships (SAR) of 14 crown and aza-crown ether analogues on five tumor-cell types. The most active compounds were di-tert-butyldicyclohexano-18-crown-6 (3), which exhibited cytotoxicity in the submicromolar range, and di-tert-butyldibenzo-18-crown-6 (5) (IC50
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