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220558

2-氨基-4-噻唑乙酸乙酯

Name: 2-氨基-4-噻唑乙酸乙酯
Brand: ALDRICH

99%

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About This Item

經驗公式（希爾表示法）:

C₇H₁₀N₂O₂S

CAS號碼:

53266-94-7

分子量：:

186.23

Beilstein:

139617

EC號碼:

258-452-1

MDL號碼:

MFCD00005330

分類程式碼代碼:

12352100

PubChem物質ID:

24853177

NACRES:

NA.22

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Slide 1 of 1

1 of 1

Sigma-Aldrich

283657

乙酰丙酮镍(II)

品質等級

200

化驗

99%

mp

92-94 °C (lit.)

官能基

ester

SMILES 字串

CCOC(=O)Cc1csc(N)n1

InChI

1S/C7H10N2O2S/c1-2-11-6(10)3-5-4-12-7(8)9-5/h4H,2-3H2,1H3,(H2,8,9)

InChI 密鑰

SHQNGLYXRFCPGZ-UHFFFAOYSA-N

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一般說明

Ethyl 2-aminothiazole-4-acetate is an organic ligand and possess strong coordination ability and display diverse coordination modes due to the presence of N, O coordination atoms.

應用

Ethyl 2-aminothiazole-4-acetate was used in the synthesis of:

bis (2-aminothiazole-4-acetato)aquazinc(II)
dichloridobis[ethyl 2-(2-amino-1, 3-thiazol-4-yl) acetate-κ²O,N³]cadmium
novel heteroaryl-containing benzamide derivatives

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

365.0 °F - closed cup

閃點（°C）

185 °C - closed cup

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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分析證明 (COA)

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Bis(2-amino-thia-zole-4-acetato)aquazinc(II).

Lai-Jun Zhang et al.

Acta crystallographica. Section E, Structure reports online, 65(Pt 12), m1517-m1517 (2009-01-01)

In the title compound, [Zn(C(5)H(5)N(2)O(2)S)(2)(H(2)O)], the central Zn atom (2 site symmetry) is five-coordinated by two N and three O atoms [Zn-N = 2.047 (3) Å, Zn-O = 2.099 (2) and 1.974 (4) Å] in a distorted square-pyramidal geometry. Besides one O atom from a

Dichloridobis[ethyl 2-(2-amino-1,3-thia-zol-4-yl)acetate-κ(2)O,N(3)]cadmium.

Lai-Jun Zhang et al.

Acta crystallographica. Section E, Structure reports online, 68(Pt 6), m788-m789 (2012-06-22)

The asymmetric unit of the title compound, [CdCl(2)(C(7)H(10)N(2)O(2)S)(2)], contains two complex molecules with similar configurations. The Cd(II) atoms are each six-coordinated by two thiazole N and two carbonyl O atoms from the 2-(2-amino-1,3-thiazol-4-yl)acetate ligand, and by two Cl(-) anions in

Discovery of 3-(4-methanesulfonylphenoxy)-N-[1-(2-methoxy-ethoxymethyl)-1H-pyrazol-3-yl]-5-(3-methylpyridin-2-yl)-benzamide as a novel glucokinase activator (GKA) for the treatment of type 2 diabetes mellitus.

Kaapjoo Park et al.

Bioorganic & medicinal chemistry, 22(7), 2280-2293 (2014-03-05)

Novel heteroaryl-containing benzamide derivatives were synthesized and screened using an in vitro assay measuring increases in glucose uptake and glucokinase activity stimulated by 10mM glucose in rat hepatocytes. From a library of synthesized compounds, 3-(4-methanesulfonylphenoxy)-N-[1-(2-methoxy-ethoxymethyl)-1H-pyrazol-3-yl]-5-(3-methyl pyridin-2-yl)-benzamide (19e) was identified as

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