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Key Documents

217719

Sigma-Aldrich

4-氨基-2-氯苯甲酸

97%

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About This Item

線性公式:
H2NC6H3(Cl)CO2H
CAS號碼:
分子量::
171.58
Beilstein:
2803668
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

97%

反應適用性

reaction type: solution phase peptide synthesis

mp

211 °C (dec.) (lit.)

應用

peptide synthesis

SMILES 字串

Nc1ccc(C(O)=O)c(Cl)c1

InChI

1S/C7H6ClNO2/c8-6-3-4(9)1-2-5(6)7(10)11/h1-3H,9H2,(H,10,11)

InChI 密鑰

MBDUKNCPOPMRJQ-UHFFFAOYSA-N

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


分析證明 (COA)

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E H Philipson et al.
American journal of obstetrics and gynecology, 151(3), 322-324 (1985-02-01)
Amide-linked local anesthetic agents, such as lidocaine and bupivacaine, can become "trapped" in their ionized forms on the fetal side of the placenta, and therefore their net transfer across the placenta is increased. An ester-linked local anesthetic agent, 2-chloroprocaine, is
B R Kuhnert et al.
Anesthesia and analgesia, 62(12), 1089-1094 (1983-12-01)
Little is known about the pharmacology of the metabolites of 2-chloroprocaine in obstetrical patients. The primary objective of this study was to describe the elimination of 2-chloroaminobenzoic acid (CABA) in maternal and neonatal urine after epidural anesthesia. A secondary objective
R R Weiss et al.
Anesthesia and analgesia, 62(2), 168-173 (1983-02-01)
2-Chloroprocaine (CP) has recently been recommended as a less toxic alternative to amide-type local anesthetics due to its rapid metabolism. A double-blind, randomized study comparing CP to lidocaine when used for paracervical block was carried out. Twenty-nine patients received CP
K Krohg et al.
Anesthesiology, 54(4), 329-332 (1981-04-01)
The purpose of this study was to identify the metabolic pathway of 2-chloro-4-aminobenzoic acid (CABA), a primary metabolite of chloroprocaine. Urine was collected from 4 healthy, pregnant women following the epidural administration of 600 mg chloroprocaine. The urinary metabolites were
P K Janicki et al.
Journal of chromatography. B, Biomedical applications, 675(2), 336-341 (1996-01-26)
A sensitive and specific high-performance liquid chromatographic method for determination of the 2-chloroprocaine, local anesthetic of ester type, and its major metabolite 2-chloroaminobenzoic acid, has been developed and validated. A single-step extraction procedure is employed followed by high-performance liquid chromatographic

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