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202487

Sigma-Aldrich

聚乙二醇甲基醚

average MN 550, methoxy, hydroxyl

同義詞:

mPEG, 甲氧基聚乙二醇, 聚乙二醇单甲醚

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About This Item

線性公式:
CH3(OCH2CH2)nOH
CAS號碼:
9004-74-4
MDL號碼:
MFCD00084416
分類程式碼代碼:
12162002
PubChem物質ID:
24852066
NACRES:
NA.23

product name

聚乙二醇甲基醚, average Mn 550

蒸汽密度

>1 (vs air)

品質等級

200

蒸汽壓力

0.05 mmHg ( 20 °C)

形狀

semisolid

分子量

average Mn 550

折射率

n20/D 1.455

黏度

7.5 cSt(210 °F)(lit.)

轉變溫度

Tm 20 °C

密度

1.089 g/mL at 25 °C

Ω-end

hydroxyl

α-end

methoxy

InChI

1S/C3H8O2/c1-5-3-2-4/h4H,2-3H2,1H3

InChI 密鑰

XNWFRZJHXBZDAG-UHFFFAOYSA-N

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相關類別

應用

聚（乙二醇）甲基醚可作为成孔剂， 以制备亲水性增强的聚砜膜。

聚（乙二醇）甲基醚接枝的聚酰胺 （PAMAM）树枝状聚合物可作为抗癌药物的 载药体系。

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

359.6 °F - closed cup

閃點（°C）

182 °C - closed cup

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分析證明 (COA)

Lot/Batch Number
MKCN8241
MKCL2387
MKCH8837
MKCF0413
MKCB0160V

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Sigma-Aldrich

8.14171

聚乙二醇二甲醚500

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International journal of pharmaceutics, 436(1-2), 183-193 (2012-06-23)
Efficacy of anticancer drug is limited by the severe adverse effects induced by drug; therefore the crux is in designing delivery systems targeted only to cancer cells. Toward this objectives, we propose, synthesis of poly(ethylene glycol) (PEG)-doxorubicin (DOX) prodrug conjugates
Mark G P Saifer et al.
Molecular immunology, 57(2), 236-246 (2013-11-10)
The use of methoxypoly(ethylene glycol) (mPEG) in PEG conjugates of proteins and non-protein therapeutic agents has led to the recognition that the polymer components of such conjugates can induce anti-PEG antibodies (anti-PEGs) that may accelerate the clearance and reduce the
Jiani Zheng et al.
Langmuir : the ACS journal of surfaces and colloids, 28(37), 13261-13273 (2012-08-28)
Alginate/chitosan/alginate (ACA) hydrogel microcapsules were modified with methoxy poly(ethylene glycol) (MPEG) to improve protein repellency and biocompatibility. Increased MPEG surface graft density (n(S)) on hydrogel microcapsules was achieved by controlling the grafting parameters including the buffer layer substrate, membrane thickness
Mulu Z Tesfay et al.
Journal of virology, 87(7), 3752-3759 (2013-01-18)
We are developing oncolytic vesicular stomatitis viruses (VSVs) for systemic treatment of multiple myeloma, an incurable malignancy of antibody-secreting plasma cells that are specifically localized in the bone marrow. One of the presumed advantages for using VSV as an oncolytic
Seung-Young Lee et al.
Biomaterials, 34(2), 552-561 (2012-10-20)
Although targeted delivery mediated by ligand modified or tumor microenvironment sensitive nanocarriers has been extensively pursued for cancer chemotherapy, the efficiency is still limited by premature drug release after systemic administration. Herein we report a highly blood-stable, tumor-adaptable drug carrier
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