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About This Item
經驗公式(希爾表示法):
C8H16N2O2
CAS號碼:
分子量::
172.22
Beilstein:
388597
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
推薦產品
化驗
96%
形狀
liquid
折射率
n20/D 1.483 (lit.)
密度
1.004 g/mL at 25 °C (lit.)
SMILES 字串
CCOC(=O)N1CCC(N)CC1
InChI
1S/C8H16N2O2/c1-2-12-8(11)10-5-3-7(9)4-6-10/h7H,2-6,9H2,1H3
InChI 密鑰
GQQQULCEHJQUJT-UHFFFAOYSA-N
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應用
Ethyl 4-amino-1-piperidinecarboxylate (1-Carbethoxy-4-aminopiperidine) was used in the synthesis of quinolin-2(1H )-one derivatives.
Reactant for synthesis of:
Milrinone analogs to analyze effects on intracellular calcium increase in cardiac cells
Tetrahydronaphthalene derivatives
Quorum sensing modulators
Selective anti-Helicobacter pylori activity molecules
Orally active M1 mAChR agonists
Aza derivatives of phytoalexin for antibacterial activity
Milrinone analogs to analyze effects on intracellular calcium increase in cardiac cells
Tetrahydronaphthalene derivatives
Quorum sensing modulators
Selective anti-Helicobacter pylori activity molecules
Orally active M1 mAChR agonists
Aza derivatives of phytoalexin for antibacterial activity
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 3
閃點(°F)
172.4 °F - closed cup
閃點(°C)
78 °C - closed cup
個人防護裝備
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Christopher Blackburn et al.
Bioorganic & medicinal chemistry letters, 16(10), 2621-2627 (2006-03-10)
Several potent, functionally active MCHr1 antagonists derived from quinolin-2(1H)-ones and quinazoline-2(1H)-ones have been synthesized and evaluated. Pyridylmethyl substitution at the quinolone 1-position results in derivatives with low-nM binding potency and good selectivity with respect to hERG binding.
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