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Merck
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重要文件

185663

Sigma-Aldrich

5-氟-1-茚酮

99%

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About This Item

經驗公式(希爾表示法):
C9H7FO
CAS號碼:
分子量::
150.15
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22
形狀:
solid
化驗:
99%

品質等級

化驗

99%

形狀

solid

bp

113-114 °C (lit.)

mp

38-40 °C (lit.)

密度

1.216 g/mL at 25 °C (lit.)

官能基

fluoro
ketone

SMILES 字串

Fc1ccc2C(=O)CCc2c1

InChI

1S/C9H7FO/c10-7-2-3-8-6(5-7)1-4-9(8)11/h2-3,5H,1,4H2

InChI 密鑰

WVPPBVAMKNQXJA-UHFFFAOYSA-N

應用

5-Fluoro-1-indanone was used to prepare precursor for thiosemicarbazones derived from 1-indanones. It was used in the synthesis of 6-fluoro-1,2,3,4-tetrahydroquinoline hydrochloride.

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

235.4 °F - closed cup

閃點(°C)

113 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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María E Caputto et al.
Bioorganic & medicinal chemistry, 19(22), 6818-6826 (2011-10-18)
In the present work, we synthesized a series of thiosemicarbazones derived from 1-indanones with good anti-Trypanosoma cruzi activity. Most of them displayed remarkable trypanosomicidal activity. All the compounds showed nonspecific cytotoxicity on human erythrocytes. The ability of the new compounds
Satoshi Sakami et al.
Bioorganic & medicinal chemistry, 16(17), 7956-7967 (2008-08-15)
We have previously reported on antitussive effect of (5R,9R,13S,14S)-17-cyclopropylmethyl-6,7-didehydro-4,5-epoxy-5',6'-dihydro-3-methoxy-4'H-pyrrolo[3,2,1-ij]quinolino[2',1':6,7]morphinan-14-ol(1b) methanesulfonate (TRK-850), a selective delta opioid receptor antagonist which markedly reduced the number of coughs in a rat cough model. We designed TRK-850 based on naltrindole (NTI), a typical delta opioid

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