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Key Documents

184756

Sigma-Aldrich

4-苯基-1-丁醇

99%

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About This Item

線性公式:
C6H5(CH2)4OH
CAS號碼:
分子量::
150.22
Beilstein:
2042122
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

形狀

liquid

折射率

n20/D 1.521 (lit.)

bp

140-142 °C/14 mmHg (lit.)

密度

0.984 g/mL at 20 °C (lit.)

官能基

hydroxyl
phenyl

SMILES 字串

OCCCCc1ccccc1

InChI

1S/C10H14O/c11-9-5-4-8-10-6-2-1-3-7-10/h1-3,6-7,11H,4-5,8-9H2

InChI 密鑰

LDZLXQFDGRCELX-UHFFFAOYSA-N

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一般說明

用硝酸铈铵乙腈溶液氧化 4-苯基-1-丁醇,得到 2-苯基四氢呋喃 。在磷酸存在下高温环化生成四氢萘

應用

4-苯基-1-丁醇被用于合成 NK105,一种含紫杉醇的胶束纳米颗粒制剂

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

230.0 °F - closed cup

閃點(°C)

110 °C - closed cup

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Paclitaxel (PTX) is one of the most effective anticancer agents. In clinical practice, however, high incidences of adverse reactions of the drug, for example, neurotoxicity, myelosuppression, and allergic reactions, have been reported. NK105, a micellar nanoparticle formulation, was developed to
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