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重要文件

149225

Sigma-Aldrich

二丙基二硫

98%

同義詞:

二丙基二硫醚

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About This Item

線性公式:
CH3CH2CH2SSCH2CH2CH3
CAS號碼:
分子量::
150.31
Beilstein:
969200
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

形狀

liquid

折射率

n20/D 1.497 (lit.)

bp

195-196 °C (lit.)

mp

−86 °C (lit.)

密度

0.96 g/mL at 25 °C (lit.)

官能基

disulfide

SMILES 字串

CCCSSCCC

InChI

1S/C6H14S2/c1-3-5-7-8-6-4-2/h3-6H2,1-2H3

InChI 密鑰

ALVPFGSHPUPROW-UHFFFAOYSA-N

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一般說明

二丙基二硫化物 (DPDS) 在 HL-60 和 HepG2 细胞中浓度较低,是一种有效的活性氧 (ROS) 清除剂 。防止 N-亚硝基哌啶 (NPIP) 和 N-亚硝基二丁胺 (NDBA) 引起的 DNA 氧化损伤

象形圖

Exclamation markEnvironment

訊號詞

Warning

危險分類

Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

147.2 °F - closed cup

閃點(°C)

64 °C - closed cup

個人防護裝備

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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C Teyssier et al.
Drug metabolism and disposition: the biological fate of chemicals, 28(6), 648-654 (2000-05-23)
The metabolism of dipropyl disulfide (DPDS), an Allium sulfur compound, was investigated in rat liver cell subfractions and in an isolated perfused rat liver. DPDS is oxidized to dipropyl thiosulfinate (DPDSO) by rat microsomes. The contribution of cytochrome P450 enzymes
Han-Seung Shin et al.
Journal of agricultural and food chemistry, 50(26), 7684-7690 (2002-12-12)
Organosulfur compounds and sodium bisulfite significantly inhibited (P < 0.05) heterocyclic aromatic amine (HAA) formation in model systems containing phenylalanine, creatinine, and glucose. There was, however, no inhibition by the same compounds in a model system containing only phenylalanine and
S G Sundaram et al.
Biochimica et biophysica acta, 1315(1), 15-20 (1996-01-17)
Diallyl disulfide (DADS), an oil-soluble organosulfur compound in processed garlic, was more effective in inhibiting the in vitro growth of human tumor cell lines: HCT-15 (colon), A549 (lung), and SK MEL-2 (skin) than isomolar quantities of the water-soluble compound S-allyl
Opender Koul
Journal of economic entomology, 97(3), 1142-1147 (2004-07-29)
Head space volatiles, including 73% di-n-propyl disulfide, were collected from freshly crushed neem seeds. This compound along with previously reported diallyl disulfide (di-2-propenyl disulfide) were toxic when applied topically or as a fumigant to Tribolium castaneum adults and 8-, 12-
Małgorzata Iciek et al.
European journal of pharmacology, 569(1-2), 1-7 (2007-06-15)
The present in vivo studies demonstrated that diallyl disulfide (DADS), occurring in garlic, elevated hepatic sulfane sulfur level and activities of gamma-cystathionase and 3-mercaptopyruvate sulfotransferase in healthy mice but did not affect the hepatic glutathione level. DADS efficiently corrected the

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