146293

(4-氟苯甲酰)乙酸乙酯

• 同義詞: 对氟苯甲酰乙酸乙酯
• 線性公式: FC₆H₄COCH₂CO₂C₂H₅
• CAS號碼: 1999-00-4
• 分子量：: 210.20
• MDL號碼: MFCD03093631
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24848775
• NACRES: NA.22

屬性

• 折射率: n20/D 1.5040 (lit.)
• 品質等級: 100
• bp: 117-120 °C (lit.)
• 密度: 1.174 g/mL at 25 °C (lit.)
• 官能基: ester; fluoro; ketone
• SMILES 字串: CCOC(=O)CC(=O)c1ccc(F)cc1
• InChI: 1S/C11H11FO3/c1-2-15-11(14)7-10(13)8-3-5-9(12)6-4-8/h3-6H,2,7H2,1H3
• InChI 密鑰: SJUXLKYJKQBZLM-UHFFFAOYSA-N

描述

一般說明

Ethyl (4-fluorobenzoyl)acetate on condensation with benzofurazan oxide yields 2-(carboethoxy)-3-(4′-fluoro)phenylquinoxaline1,4-dioxide.

應用

Reactant used as a precursor in:

• Condensation reactions with diamines via C-C bond cleavage for synthesis of benzimidazoles and perimidines for possible use as antimalarial treatments
• Base-promoted domino Michael addition / cyclization / elimination reactions for synthesis of hydroxybenzophenones
• Oxidative cross-coupling with indoles via dioxygen activation
• Cyclization of keto esters for synthesis of pyrones
• Lewis base catalyzed hydrosilylation for synthesis of α-acetoxy β-amino acid derivatives
• Conia-ene reactions for synthesis of methylenecyclopentane derivatives

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves