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Merck
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重要文件

142875

Sigma-Aldrich

2,6-吡啶二甲酰氯

97%

同義詞:

2,6-吡啶二羰酰氯, 2,6-氯甲酰吡啶

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About This Item

經驗公式(希爾表示法):
C7H3Cl2NO2
CAS號碼:
分子量::
204.01
Beilstein:
131556
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

97%

形狀

solid

bp

284 °C (lit.)

mp

56-58 °C (lit.)

官能基

acyl chloride

SMILES 字串

ClC(=O)c1cccc(n1)C(Cl)=O

InChI

1S/C7H3Cl2NO2/c8-6(11)4-2-1-3-5(10-4)7(9)12/h1-3H

InChI 密鑰

GWHOGODUVLQCEB-UHFFFAOYSA-N

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應用

2.6-吡啶二羰基二氯化物可用作合成以下物质的起始材料:
  • 吡啶基聚酰胺聚酯,与手性二氢溴化二胺反应形成光学活性大环化合物。
  • 吡啶桥联 2,6-双-甲酰胺席夫′碱,采用L-丙氨酸或2- 甲基-丙氨酸甲酯进行处理。
  • N,N′-双(1-芘甲基)吡啶-2,6-二羧酰胺,在存在碱的条件下与1-芘甲基胺盐酸盐反应。

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Skin Sens. 1A

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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H Zhao et al.
The Journal of organic chemistry, 65(10), 2933-2938 (2000-05-18)
Five new chiral macrocycles, 3a-e, have been prepared by the acylation cyclization of chiral diamine dihydrobromide intermediates 2a-c with 2,6-pyridinedicarbonyl dichloride in highly diluted solution at room temperature. The chiral diesters 1a-c needed for the preparation of the macrocycles were
Mohamed A Al-Omar et al.
Molecules (Basel, Switzerland), 15(7), 4711-4721 (2010-07-27)
A series of pyridine-bridged 2,6-bis-carboxamide Schiff's bases has been prepared starting from 2,6-pyridinedicarbonyl dichloride (1) and L-alanine or 2-methyl-alanine methyl ester.The coupling of acid chloride 1 with L-alanine methyl ester hydrochloride -or 2-methylalanine methyl ester hydrochloride gave the corresponding 2,6-bis-carboxamide
Synthesis of some new pyridine-2, 6-carboxamide-derived Schiff bases as potential antimicrobial agents
Al-Omar MA and Amr Abd El-Galil E
Molecules (Basel), 15(7), 4711-4721 (2010)
Howard M Colquhoun et al.
Faraday discussions, 143, 205-220 (2009-01-01)
A novel type of tweezer molecule containing electron-rich 2-pyrenyloxy arms has been designed to exploit intramolecular hydrogen bonding in stabilising a preferred conformation for supramolecular complexation to complementary sequences in aromatic copolyimides. This tweezer-conformation is demonstrated by single-crystal X-ray analyses

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