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Key Documents

133973

Sigma-Aldrich

溴乙酸乙酯

reagent grade, 98%

同義詞:

Bromoacetic acid ethyl ester, Ethyl 2-bromoacetate

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About This Item

線性公式:
BrCH2COOC2H5
CAS號碼:
分子量::
167.00
Beilstein:
506456
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

等級

reagent grade

蒸汽壓力

2.6 mmHg ( 25 °C)

化驗

98%

形狀

liquid

折射率

n20/D 1.451 (lit.)

bp

159 °C (lit.)

溶解度

water: insoluble

密度

1.506 g/mL at 25 °C (lit.)

官能基

bromo

SMILES 字串

CCOC(=O)CBr

InChI

1S/C4H7BrO2/c1-2-7-4(6)3-5/h2-3H2,1H3

InChI 密鑰

PQJJJMRNHATNKG-UHFFFAOYSA-N

尋找類似的產品? 前往 產品比較指南

一般說明

溴代乙酸乙酯常在有机合成中用作为烷化剂和酰化试剂。溴代乙酸乙酯与叔丁基杯[4]芳烃进行衍生化反应,生成1,3-二酯取代的杯[4]芳烃。它还与芳基硼酸在氧化铜(I)共催化下发生Suzuki型交叉偶联反应

應用

溴乙酸乙酯用于在水性介质中制备可逆光敏香豆素稳定的聚合物纳米颗粒,其可用作可检测的药物载体

象形圖

FlameSkull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Flam. Liq. 3

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

116.6 °F - closed cup

閃點(°C)

47 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Gillian McMahon et al.
Talanta, 57(6), 1119-1132 (2008-10-31)
A series of derivatisation reactions between p-t-butyl calix[4]arene and ethyl bromoacetate were carried out in order to prepare 1,3 diester substituted calix[4]arene. Mass spectral data, obtained from direct injection of samples, indicated that the reactions were rich in the desired
Jae Woo Chung et al.
Small (Weinheim an der Bergstrasse, Germany), 8(11), 1693-1700 (2012-03-29)
The ability to create aqueous suspended stable nanoparticles of the hydrophobic homopolymer poly(ϵ-caprolactone) end-functionalized with coumarin moieties (CPCL) is demonstrated. Nanoparticles of CPCL are prepared in a continuous manner using nanoprecipitation. The resulting nanoparticles are spherical in morphology, about 40
Occupational allergic contact dermatitis in a chemist from ethyl bromoacetate and bromoacetonitrile.
B Hernández-Machín et al.
Contact dermatitis, 52(2), 115-116 (2005-02-24)
Xing-xin Liu et al.
Chemical communications (Cambridge, England), (6)(6), 622-623 (2002-07-18)
Copper(I) oxide can effectively co-catalyze the Suzuki type cross-coupling reactions of arylboronic acids with ethyl bromoacetate. As an alternative protocol for introducing the methylenecarboxy group into functionalized molecules, this reaction occurs in the absence of highly toxic thallium compounds or
Yaser A-H Mostafa et al.
Archives of pharmacal research, 31(3), 279-293 (2008-04-15)
Certain new derivatives of 1,2,4-triazolo[1,5-a]pyrimidines were synthesized through the reaction of 1,2,4-triazolo[1,5-a]pyrimidine-7-ol with ethyl bromoacetate to afford the ethyl acetate ester, which upon hydrazinolysis gives the corresponding hydrazide. The hydrazide is the key intermediate which was used for the synthesis

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