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132195

Sigma-Aldrich

磷酸三甲酯

97%

同義詞:

TMP, TMPA, TMPO

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About This Item

線性公式:
(CH3O)3PO
CAS號碼:
分子量::
140.07
Beilstein:
1071731
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

97%

形狀

liquid

折射率

n20/D 1.395 (lit.)

bp

197 °C (lit.)

mp

−46 °C (lit.)

密度

1.197 g/mL at 25 °C (lit.)

SMILES 字串

COP(=O)(OC)OC

InChI

1S/C3H9O4P/c1-5-8(4,6-2)7-3/h1-3H3

InChI 密鑰

WVLBCYQITXONBZ-UHFFFAOYSA-N

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相關類別

一般說明

磷酸三甲酯是一种良好的偶极非质子溶剂,可用作多种有机转化反应中的甲基化剂和酸清除剂。

應用

磷酸三甲酯可用作以下反应的甲基化剂:
  • 酚类化合物的无溶剂o-甲基化反应以合成甲基芳基醚。
  • 在 Ca(OH)2 碱存在的情况下进行芳基/烷基硫醇的S-甲基化反应合成S-甲基化产物。

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 1

閃點(°F)

302.0 °F - closed cup

閃點(°C)

150 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


分析證明 (COA)

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Hydrolysis of acetyl dimethyl phosphate, a reactive acyl phosphate.
R Kluger et al.
Biochemistry, 11(8), 1544-1546 (1972-04-11)
Yongqing Ma et al.
Analytica chimica acta, 786, 47-53 (2013-06-26)
An analytical method for the determination of 14 organophosphorus flame retardants (OPFRs), including halogenated OPFRs, non-halogenated OPFRs and triphenyl phosphine oxide (TPPO) in biological samples was developed using gas chromatography-mass spectrometry (GC/MS). Biological samples were extracted using microwave-assisted extraction (MAE)
Qingguo Meng et al.
Environmental science & technology, 45(7), 3000-3005 (2011-03-03)
Due to the neurotoxicity of organophosphate (OP) pesticides and nerve agents synthesized as military or terror agents, their safe destruction and disposal is of considerable current importance. A representative OP, trimethyl phosphate (TMP), was adsorbed onto NaX zeolite, two mesoporous
Johannes Bernarding et al.
Journal of the American Chemical Society, 128(3), 714-715 (2006-01-19)
In ultralow magnetic fields, liquid state nuclear magnetic resonance (NMR) spectra of homonuclear spin systems exhibit line widths dominated by their natural lifetime. Chemical shifts become negligible, and heteronuclear NMR spectra show predominantly the electron-mediated field-independent J-coupling. However, weak polarization
Chunhai Ruan et al.
Journal of the American Society for Mass Spectrometry, 19(2), 305-314 (2008-04-15)
Threshold collision-induced dissociation techniques are employed to determine the bond dissociation energies (BDEs) of complexes of alkali metal cations to trimethyl phosphate, TMP. Endothermic loss of the intact TMP ligand is the only dissociation pathway observed for all complexes. Theoretical

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