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Key Documents

121967

Sigma-Aldrich

氨基乙醛缩二甲醇

99%

同義詞:

2,2-二甲氧基乙胺

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About This Item

線性公式:
NH2CH2CH(OCH3)2
CAS號碼:
分子量::
105.14
Beilstein:
741868
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

99%

折射率

n20/D 1.417 (lit.)

bp

135-139 °C/95 mmHg (lit.)

密度

0.965 g/mL at 25 °C (lit.)

官能基

acetal

SMILES 字串

COC(CN)OC

InChI

1S/C4H11NO2/c1-6-4(3-5)7-2/h4H,3,5H2,1-2H3

InChI 密鑰

QKWWDTYDYOFRJL-UHFFFAOYSA-N

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一般說明

氨基乙醛缩二甲醇与砜反应,然后加入所需的哌嗪衍生物进行水解和还原胺化反应,从而产生2-呋喃基[1,2,4]三唑并[1,5-a][1,3,5]三嗪的哌嗪衍生物.

氨基乙醛二甲基缩醛可用作合成各种酰化和磺化氧代烯酰胺(oxyenamide)的合成砌块。

應用

氨基乙醛缩二甲醇被用于开发醛脱氢酶的荧光底物。它被用于制备具有羧基、酯和聚乙二醇等各种官能团的壳聚糖-树枝状大分子杂化物。它被用于从 L-抗坏血酸 合成双环脯氨酸类似物的高效3步合成法,并用于MgClO4 催化的三组分反应,得到α-氨基膦酸盐

象形圖

FlameCorrosion

訊號詞

Danger

危險聲明

危險分類

Flam. Liq. 3 - Skin Corr. 1B

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

111.2 °F - closed cup

閃點(°C)

44 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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Hitoshi Sashiwa et al.
Biomacromolecules, 4(5), 1244-1249 (2003-09-10)
Chitosan-dendrimer hybrids having various functional groups such as carboxyl, ester, and poly(ethylene glycol) groups were prepared successfully using dendrimer acetal by reductive N-alkylation. The synthetic procedure could be accomplished by one-step reaction without organic solvent. The degree of substitution of
R W Storms et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(16), 9118-9123 (1999-08-04)
Because hematopoietic stem cells are rich in aldehyde dehydrogenase (ALDH) activity, we developed a fluorescent substrate for ALDH, termed BODIPY aminoacetaldehyde (BAAA), and tested its potential for isolating primitive human hematopoietic cells. A population of cells with low orthogonal light
Chi B Vu et al.
Bioorganic & medicinal chemistry letters, 14(19), 4835-4838 (2004-09-03)
Piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine have recently been shown to be potent and selective adenosine A(2a) receptor antagonists. We now demonstrate that potent and selective A(2a) receptor antagonists could still be obtained when the arylpiperazines are separated from the triazolotriazine core
Synthesis, 3122-3122 (2006)
Maria C Llinàs et al.
Drug delivery, 25(1), 1137-1146 (2018-05-22)
A dual doxorubicin/camptothecin (DOX/CPT) pH-triggered drug delivery mesoporous silica nanoparticle (MSN)-based nano-vehicle has been prepared. In this drug-delivery system (DDS), CPT is loaded inside the pores of the MSNs, while DOX is covalently attached to the surface of an aldehyde-functionalized

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