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Merck
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重要文件

118559

Sigma-Aldrich

1,5-己二烯-3-醇

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About This Item

線性公式:
H2C=CHCH2CH(OH)CH=CH2
CAS號碼:
分子量::
98.14
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

折射率

n20/D 1.448 (lit.)

密度

0.878 g/mL at 25 °C (lit.)

官能基

allyl
hydroxyl

SMILES 字串

OC(CC=C)C=C

InChI

1S/C6H10O/c1-3-5-6(7)4-2/h3-4,6-7H,1-2,5H2

InChI 密鑰

SZYLTIUVWARXOO-UHFFFAOYSA-N

一般說明

1,5-Hexadien-3-ol is the starting reagent for the enantioselective synthesis of (+)-rogioloxepane A. It undergoes Sharpless kinetic resolution and ring-closing metathesis to yield nine membered oxocene.

應用

1,5-Hexadien-3-ol was used in the synthesis of (+)-obtusenyne.

象形圖

Flame

訊號詞

Warning

危險聲明

危險分類

Flam. Liq. 3

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 3

閃點(°F)

84.2 °F - closed cup

閃點(°C)

29 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Journal of the American Chemical Society, 125(25), 7592-7595 (2003-06-19)
A total synthesis of the laurencia metabolite (+)-obtusenyne has been completed. The key steps include a Sharpless kinetic resolution and an asymmetric glycolate alkylation to establish the stereogenic centers adjacent to the ether linkage and a ring-closing metathesis reaction to
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