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重要文件

112968

Sigma-Aldrich

甲基氢醌

99%

同義詞:

邻甲基对苯二酚

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About This Item

線性公式:
CH3C6H3-1,4-(OH)2
CAS號碼:
分子量::
124.14
Beilstein:
2041489
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

99%

形狀

solid

自燃溫度

851 °F

mp

128-130 °C (lit.)

SMILES 字串

Cc1cc(O)ccc1O

InChI

1S/C7H8O2/c1-5-4-6(8)2-3-7(5)9/h2-4,8-9H,1H3

InChI 密鑰

CNHDIAIOKMXOLK-UHFFFAOYSA-N

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一般說明

甲基对苯二酚通过突变体 G103S、G103S/A107G 和 G103S/A107T 氧化邻甲酚生成

應用

甲基氢醌可用作制备以下物质的反应物:
  • 通过与 4,4′-癸二酰二氧基二苯甲酰氯的缩聚反应制备的半柔性热致聚酯。
  • 倍半萜烯 (±)-向日葵叶醇A。
  • 与六氯环三磷腈反应制备的聚{六[(甲基)(4-羟基苯氧基)]环三磷腈}。
  • 在H2SO4 催化剂存在的情况下以乙酰乙酸乙酯处理制备的6-羟基-4,7-二甲基-2H-1-苯并吡喃-2-酮。

生化/生理作用

甲基对苯二酚(甲苯醌)在微摩尔范围内抑制培养的内皮细胞和肿瘤细胞的生长,是治疗癌症和其他血管生成相关病理的一个有前途的候选药物

訊號詞

Danger

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

8A - Combustible corrosive hazardous materials

水污染物質分類(WGK)

WGK 2

閃點(°F)

341.6 °F - closed cup

閃點(°C)

172 °C - closed cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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C Schewe et al.
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Van Duy Nguyen et al.
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C Furihata et al.
Japanese journal of cancer research : Gann, 84(3), 223-229 (1993-03-01)
The possible tumor-promoting and tumor-initiating activities of p-methylcatechol and methylhydroquinone in the pyloric mucosa of male F344 rats were studied. Ornithine decarboxylase (ODC) and replicative DNA synthesis (RDS) were used as markers of tumor promotion and DNA single strand scission

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