推薦產品
等級
produced by Wacker Chemie AG, Burghausen, Germany
品質等級
化驗
≥86.5% (GC)
bp
88-90 °C/76 mmHg (lit.)
mp
9-11 °C (lit.)
密度
1.512 g/mL at 20 °C (lit.)
官能基
chloro
ketone
SMILES 字串
ClCC(=O)C(Cl)Cl
InChI
1S/C3H3Cl3O/c4-1-2(7)3(5)6/h3H,1H2
InChI 密鑰
ZWILTCXCTVMANU-UHFFFAOYSA-N
尋找類似的產品？ 前往 產品比較指南
一般說明
1,1,3-Trichloroacetone is direct-acting mutagens in the Ames/Salmonella assay. It is precursor for the generation of 1,3-dihalo oxyallyl intermediates, which undergo [4 + 3] cycloadditions with a host of 1,3-diene systems.
應用
1,1,3-Trichloroacetone was used in base-induced solvolyses of [3.2.1]Bicyclic α,α′-dichloro ketones.
其他說明
根据要求提供批量采购价
訊號詞
Danger
危險分類
Acute Tox. 1 Inhalation - Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B
水污染物質分類（WGK）
WGK 3
個人防護裝備
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Base-Induced Solvolyses of [3.2. 1] Bicyclic a, a'-Dichloro Ketones- 1, 3-Transposition and Ring-Contraction.
Fohlisch B, et al.
European Journal of Organic Chemistry, 2001(22), 4357-4365 (2001)
W F Blazak et al.
Mutation research, 206(4), 431-438 (1988-12-01)
1,1,1- and 1,1,3-trichloroacetones (TCA) result from the disinfection of municipal water supplies with chlorine, and are direct-acting mutagens in the Ames/Salmonella assay. The objective of this study was to further investigate the genotoxicity of these compounds in mammalian cells using
M Robinson et al.
Cancer letters, 48(3), 197-203 (1989-12-01)
Several chlorinated acetones have been identified in drinking water and these, as well as a number of chlorinated acroleins, are produced by chlorination of humic acid solutions. Many of these chlorinated compounds and the brominated acrolein analog were positive in
Ho Lam Chan et al.
Nature communications, 9(1), 3377-3377 (2018-08-25)
Polycomb repressive complex 1 (PRC1) plays essential roles in cell fate decisions and development. However, its role in cancer is less well understood. Here, we show that RNF2, encoding RING1B, and canonical PRC1 (cPRC1) genes are overexpressed in breast cancer.
Yusheng Zhang et al.
Science advances, 6(23), eaaz7249-eaaz7249 (2020-06-18)
RING1B, a core Polycomb repressive complex 1 subunit, is a histone H2A ubiquitin ligase essential for development. RING1B is overexpressed in patients with luminal breast cancer (BC) and recruited to actively transcribed genes and enhancers co-occupied by the estrogen receptor
我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.
聯絡技術服務