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Merck
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重要文件

107271

Sigma-Aldrich

(±)-3-氯-1,2-丙二醇

98%

同義詞:

α-Monochlorohydrin, α-氯丙二醇, α-氯甘油, 3-MCPD

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About This Item

線性公式:
ClCH2CH(OH)CH2OH
CAS號碼:
分子量::
110.54
Beilstein:
635684
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

蒸汽壓力

0.04 mmHg ( 25 °C)

品質等級

化驗

98%

折射率

n20/D 1.480 (lit.)

bp

213 °C (lit.)

溶解度

H2O: soluble
alcohol: soluble
diethyl ether: soluble

密度

1.322 g/mL at 25 °C (lit.)

官能基

chloro
hydroxyl

SMILES 字串

OCC(O)CCl

InChI

1S/C3H7ClO2/c4-1-3(6)2-5/h3,5-6H,1-2H2

InChI 密鑰

SSZWWUDQMAHNAQ-UHFFFAOYSA-N

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一般說明

3-氯-1,2-丙二醇通过棒状杆菌菌株N-1074的细胞提取物进行对映选择性转化为(R)-3-氯-1,2-丙二醇。它是一种污染物,以游离(二醇)形式存在于食品中,也以酯化(用脂肪酸)形式存在于食品中

應用

(±)-3-氯-1,2-丙二醇可用于制造染料中间体。

生化/生理作用

3-氯-1,2-丙二醇是一种强效啮齿动物化学消毒剂

訊號詞

Danger

危險分類

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Carc. 2 - Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Irrit. 2 - STOT RE 1 - STOT SE 1

標靶器官

Kidney, Testes

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

235.4 °F - closed cup

閃點(°C)

113 °C - closed cup

個人防護裝備

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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分析證明 (COA)

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Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 25(4), 391-400 (2008-03-19)
3-Mono-chloropropane-1,2-diol (3-MCPD) is a contaminant that occurs in food in its free (diol) form as well as in an esterified (with fatty acids) form. Using a simple intestinal model, it was demonstrated that 3-MCPD monoesters and 3-MCPD diesters are accepted
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Sperm ATP is derived primarily from either glycolysis or mitochondrial oxidative phosphorylation. In the present studies, (1)H NMR spectroscopy was used to characterize the metabolite profile in primate sperm treated either with alpha-chlorohydrin (ACH), a known inhibitor of sperm glycolysis
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A series of twelve breast milk samples were analysed by gas chromatography-mass spectrometry (GC/MS) operated in selected ion monitoring mode for 3-chloropropane-1,2-diol (3-MCPD). Whilst none of the samples contained 3-MCPD above the limit of detection of 3 microg kg(-1) milk

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