TNFAIP3
tumor necrosis factor, alpha-induced protein 3
A20, OTUD7C, TNFA1P2
Human TNFAIP3 (7128), Mouse Tnfaip3 (21929), Rat Tnfaip3 (683206), Zebrafish tnfaip3 (564497), Horse TNFAIP3 (100073197), domestic cat TNFAIP3 (101083682), dog TNFAIP3 (484006), chicken TNFAIP3 (421684), domestic guinea pig Tnfaip3 (100720503), cow TNFAIP3 (508105)
- Human(7128) Summary: This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein and ubiqitin-editing enzyme, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. The encoded protein, which has both ubiquitin ligase and deubiquitinase activities, is involved in the cytokine-mediated immune and inflammatory responses. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2012]
- Mouse(21929) tumor necrosis factor, alpha-induced protein 3
- Rat(683206) tumor necrosis factor, alpha-induced protein 3
- Zebrafish(564497) tumor necrosis factor, alpha-induced protein 3
- Horse(100073197) tumor necrosis factor, alpha-induced protein 3
- domestic cat(101083682) tumor necrosis factor, alpha-induced protein 3
- dog(484006) tumor necrosis factor, alpha-induced protein 3
- chicken(421684) tumor necrosis factor, alpha-induced protein 3
- domestic guinea pig(100720503) tumor necrosis factor, alpha-induced protein 3
- cow(508105) tumor necrosis factor, alpha-induced protein 3
- sheep(101113156) tumor necrosis factor, alpha-induced protein 3
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