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Merck

STAT5B

signal transducer and activator of transcription 5B

同義詞:
STAT5
物種:
UniProtKB ID:
基因 ID:
  • Human(6777) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
  • Mouse(20851) signal transducer and activator of transcription 5B
  • Rat(25126) signal transducer and activator of transcription 5B
  • domestic guinea pig(100716532) signal transducer and activator of transcription 5B
  • naked mole-rat(101722721) signal transducer and activator of transcription 5B
  • cow(282376) signal transducer and activator of transcription 5B
  • sheep(101122961) signal transducer and activator of transcription 5B
  • chicken(395556) signal transducer and activator of transcription 5B
  • domestic cat(101090663) signal transducer and activator of transcription 5B
  • dog(490969) signal transducer and activator of transcription 5B

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ELISA

產品編號
描述
物種
检测培养细胞系中磷酸化STAT5 (pTyr694)的基于细胞的ELISA试剂盒, 96 assays,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-STAT5B Antibody, Upstate®, from rabbit,
物種活性
human, mouse
應用
western blot
Anti-STAT5B (ab2) antibody produced in rabbit, affinity isolated antibody,
物種活性
dog, horse, human, mouse, pig, rabbit, rat
應用
immunohistochemistry
western blot
ANTI-STAT5B antibody produced in mouse, clone 2D1, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-acetyl STAT5B (Lys701) Antibody, from rabbit, purified by affinity chromatography,
物種活性
human
應用
dot blot
western blot

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting mouse Stat5b,
物種
mouse