SIRT1
sirtuin 1
同義詞:
SIR2L1
物種:
Human SIRT1 (23411), Mouse Sirt1 (93759), Rat Sirt1 (309757), domestic guinea pig Sirt1 (100717014), naked mole-rat Sirt1 (101720282), Domestic Rabbit SIRT1 (100349271), cow SIRT1 (613629), sheep SIRT1 (101102956), Zebrafish sirt1 (797132), chicken SIRT1 (423646) ...更多
UniProtKB ID:
基因 ID:
- Human(23411) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
- Mouse(93759) sirtuin 1
- Rat(309757) sirtuin 1
- domestic guinea pig(100717014) sirtuin 1
- naked mole-rat(101720282) sirtuin 1
- Domestic Rabbit(100349271) sirtuin 1
- cow(613629) sirtuin 1
- sheep(101102956) sirtuin 1
- Zebrafish(797132) sirtuin (silent mating type information regulation 2 homolog) 1
- chicken(423646) sirtuin 1
- dog(489012) sirtuin 1
- domestic cat(101087610) sirtuin 1
- Horse(100072571) sirtuin 1
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ELISA
產品編號
描述
物種
Small Molecule - Activator
產品編號
描述
物種
Activity Assay
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描述
物種
Antibodies
產品編號
描述
物種活性
應用
抗SIRT1抗体，克隆10E4, clone 10-E-4, from mouse,
物種活性
human, mouse
應用
ChIP
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
抗-SIRT1 兔抗, affinity isolated antibody,
物種活性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot
Monoclonal Anti-SIRT1 antibody produced in mouse, clone 7B7, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-Sir2 (AS-16) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
mouse
應用
immunofluorescence
microarray
western blot
microarray
western blot
Anti-Sirt1 antibody, Mouse monoclonal, clone SIR11, purified from hybridoma cell culture,
物種活性
mouse
應用
ELISA
microarray
western blot
microarray
western blot
Small Molecule - Inhibitor
Proteins
產品編號
描述
物種
SIRT1 人, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human
SIRT1, active, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human
esiRNA
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描述
物種