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Merck

PTGER4

prostaglandin E receptor 4 (subtype EP4)

同義詞:
EP4, EP4R
物種:
Human PTGER4 (5734), Mouse Ptger4 (19219), Rat Ptger4 (84023), domestic guinea pig Ptger4 (100192398), Domestic Rabbit PTGER4 (100009081), naked mole-rat Ptger4 (101723705), cow PTGER4 (282331), sheep PTGER4 (101104343), sheep PTGER4 (443222), chicken PTGER4 (427183) ...更多
UniProtKB ID:
P35408, Q3MJ87
基因 ID:
  • Human(5734) Summary: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
  • Mouse(19219) prostaglandin E receptor 4 (subtype EP4)
  • Rat(84023) prostaglandin E receptor 4 (subtype EP4)
  • domestic guinea pig(100192398) prostaglandin E receptor 4 (subtype EP4)
  • Domestic Rabbit(100009081) prostaglandin E receptor 4 (subtype EP4)
  • naked mole-rat(101723705) prostaglandin E receptor 4 (subtype EP4)
  • cow(282331) prostaglandin E receptor 4 (subtype EP4)
  • sheep(101104343) prostaglandin E receptor 4 (subtype EP4)
  • sheep(443222) prostaglandin E receptor 4 (subtype EP4)
  • chicken(427183) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(101094734) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(100169968) prostaglandin E receptor 4 (subtype EP4)
  • dog(403589) prostaglandin E receptor 4 (subtype EP4)

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Small Molecule - Agonist

產品編號
描述
物種
1213103
前列腺素E2, United States Pharmacopeia (USP) Reference Standard,
物種
human
D2250000
前列腺素E2, European Pharmacopoeia (EP) Reference Standard,
物種
human
P5515
前列腺素 E1, ≥98% (HPLC), synthetic,
物種
human, mouse
P7527
前列腺素 E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
物種
human, mouse
P8908
前列腺素 E1, synthetic, powder, BioReagent, suitable for cell culture,
物種
human, mouse

Small Molecule - Antagonist

產品編號
描述
物種
P5515
前列腺素 E1, ≥98% (HPLC), synthetic,
物種
human, mouse
P7527
前列腺素 E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
物種
human, mouse
P8908
前列腺素 E1, synthetic, powder, BioReagent, suitable for cell culture,
物種
human, mouse
P0409
前列腺素E2, synthetic, powder, BioReagent, suitable for cell culture,
物種
human, mouse
P5640
前列腺素E2, ≥93% (HPLC), synthetic,
物種
mouse, human

Small Molecule - Mixed Agonist/Antagonist

產品編號
描述
物種
P5640
前列腺素E2, ≥93% (HPLC), synthetic,
物種
mouse, human
I7378
吲哚美辛, 98.5-100.5% (in accordance with EP),
物種
human, mouse, rat

Proteins

產品編號
描述
物種
HTS142M
ChemiScreen 膜制剂
重组人EP4前列腺素受体, Human EP4 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
物種
human