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Merck

NQO1

NAD(P)H dehydrogenase, quinone 1

同義詞:
DHQU, DIA4, DTD, NMOR1, NMORI, QR1
物種:
UniProtKB ID:
基因 ID:
  • Human(1728) Summary: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(18104) NAD(P)H dehydrogenase, quinone 1
  • Rat(24314) NAD(P)H dehydrogenase, quinone 1
  • sheep(101121876) NAD(P)H dehydrogenase, quinone 1
  • naked mole-rat(101711262) NAD(P)H dehydrogenase, quinone 1
  • domestic guinea pig(100135582) NAD(P)H dehydrogenase, quinone 1
  • Zebrafish(322506) NAD(P)H dehydrogenase, quinone 1
  • dog(610935) NAD(P)H dehydrogenase, quinone 1
  • domestic cat(101097859) NAD(P)H dehydrogenase, quinone 1
  • cow(519632) NAD(P)H dehydrogenase, quinone 1
  • chicken(769737) NAD(P)H dehydrogenase, quinone 1

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Antibodies

Product Number
描述
物種活性
應用
Anti-NQO1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunofluorescence
immunohistochemistry

western blot
Anti-NQO1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse
應用
western blot
Monoclonal Anti-NQO1 antibody produced in mouse, clone 4D12, ascites fluid,
物種活性
human
應用
ELISA
flow cytometry

immunohistochemistry

western blot
Anti-NQO1 Rabbit pAb, liquid, Calbiochem®,
物種活性
human, mouse
應用
Monoclonal Anti-NQO1 antibody produced in mouse, clone 1A11, ascites fluid,
物種活性
human
應用
ELISA
flow cytometry

western blot

Small Molecule - Inhibitor

Product Number
描述
物種
甲萘醌, crystalline,
物種
human
甲萘醌, meets USP testing specifications,
物種
human
甲萘醌 (K3), analytical standard,
物種
human

Proteins

Product Number
描述
物種
DT透明质酸酶(NQO1) 人, lyophilized powder, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
物種
human
NQO1 人, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
物種
human