MYLK
myosin light chain kinase
同義詞:
AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK
物種:
Human MYLK (4638), Mouse Mylk (107589), Rat Mylk (288057), chicken MYLK (396445), dog MYLK (488012), Horse MYLK (100070482), cow MYLK (338037), naked mole-rat Mylk (101704236), Domestic Rabbit MYLK (100009143), domestic guinea pig Mylk (100714177)
UniProtKB ID:
基因 ID:
- Human(4638) Summary: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts. [provided by RefSeq, Jul 2008]
- Mouse(107589) myosin, light polypeptide kinase
- Rat(288057) myosin light chain kinase
- chicken(396445) myosin light chain kinase
- dog(488012) myosin light chain kinase
- Horse(100070482) myosin light chain kinase
- cow(338037) myosin light chain kinase
- naked mole-rat(101704236) myosin light chain kinase
- Domestic Rabbit(100009143) myosin light chain kinase
- domestic guinea pig(100714177) myosin light chain kinase
- sheep(443334) myosin light chain kinase
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Antibodies
Product Number
描述
物種活性
應用
单克隆抗肌球蛋白轻链激酶 小鼠抗, clone K36, ascites fluid,
物種活性
avian, mammals
應用
immunoprecipitation (IP)
microarray
western blot
microarray
western blot
Anti-MYLK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse
應用
ELISA
western blot
western blot
Monoclonal Anti-MYLK antibody produced in mouse, clone 1D1, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
western blot
Anti-MYLK antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
proximity ligation assay
western blot
western blot
Small Molecule - Inhibitor
Product Number
描述
物種
Proteins
Product Number
描述
物種
MLCK Protein, active, 10 µg, Active, N-terminal 6His-tagged, recombinant, human MLCK, amino acids 1425-1771, for use in Kinase Assays.,
物種
human
MLCK (1425-1776)，活性，GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human
esiRNA
Product Number
描述
物種