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Merck

MTOR

mechanistic target of rapamycin (serine/threonine kinase)

同義詞:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
物種:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), Zebrafish mtor (324254), cow MTOR (100139219), Horse MTOR (100051341), domestic cat MTOR (101098152), dog MTOR (478232), fruit fly Mtor (36264), chicken MTOR (419455) ...更多
UniProtKB ID:
P42345, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
基因 ID:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)

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Antibodies

產品編號
描述
物種活性
應用
SAB4504476
抗 磷酸化-mTOR (pSer 2448 ) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
western blot
09-213
抗磷酸化mTOR（Ser2448）抗体, Upstate®, from rabbit,
物種活性
human
應用
western blot
05-1592
抗-mTOR抗体，克隆21D8.2, clone 2ID8.2, from mouse,
物種活性
human, mouse
應用
immunocytochemistry
western blot
SAB4301526
Anti-phospho-mTOR (pSer2481) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
western blot
SAB2702297
Monoclonal Anti-mTOR antibody produced in mouse, clone GT6611, affinity isolated antibody,
物種活性
human
應用
immunofluorescence
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
SML0120
哌克昔林 马来酸盐, ≥98% (HPLC),
物種
human

Proteins

產品編號
描述
物種
14-770-M
mTOR（1362端）蛋白，活性，10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
物種
human
SRP0364
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
物種
human