GRM2
glutamate receptor, metabotropic 2
同義詞:
GLUR2, GPRC1B, MGLUR2, mGlu2
物種:
Human GRM2 (2912), Mouse Grm2 (108068), Rat Grm2 (24415), chicken GRM2 (427575), dog GRM2 (484751), domestic cat GRM2 (101098611), cow GRM2 (519904), Horse GRM2 (100052178), sheep GRM2 (101116870), domestic guinea pig Grm2 (100720736)
UniProtKB ID:
基因 ID:
- Human(2912) Summary: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(108068) glutamate receptor, metabotropic 2
- Rat(24415) glutamate receptor, metabotropic 2
- chicken(427575) glutamate receptor, metabotropic 2
- dog(484751) glutamate receptor, metabotropic 2
- domestic cat(101098611) glutamate receptor, metabotropic 2
- cow(519904) glutamate receptor, metabotropic 2
- Horse(100052178) glutamate receptor, metabotropic 2
- sheep(101116870) glutamate receptor, metabotropic 2
- domestic guinea pig(100720736) glutamate receptor, metabotropic 2
- naked mole-rat(101722804) glutamate receptor, metabotropic 2
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Small Molecule - Agonist
Small Molecule - Antagonist
Antibodies
產品編號
描述
物種活性
應用
Anti-mGluR2/3 Antibody, Upstate®, from rabbit,
物種活性
human, rat
應用
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-MGLUR2 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Metabotropic Glutamate Receptor 2 Antibody, Chemicon®, from rabbit,
物種活性
human
應用
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-GRM2 antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-Metabotropic Glutamate Receptor 2/3 Antibody, Chemicon®, from rabbit,
物種活性
monkey, rat
應用
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Small Molecule - Ligand
產品編號
描述
物種
Small Molecule - Mixed Agonist/Antagonist
產品編號
描述
物種
L-谷氨酸, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
物種
rat, human