GRM1
glutamate receptor, metabotropic 1
同義詞:
GPRC1A, MGLU1, MGLUR1, SCAR13
物種:
Human GRM1 (2911), Mouse Grm1 (14816), Rat Grm1 (24414), domestic guinea pig Grm1 (100730891), naked mole-rat Grm1 (101712477), Domestic Rabbit GRM1 (100356201), Zebrafish grm1 (100150246), dog GRM1 (484024), domestic cat GRM1 (101094104), cow GRM1 (540485) ...更多
UniProtKB ID:
基因 ID:
- Human(2911) Summary: This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
- Mouse(14816) glutamate receptor, metabotropic 1
- Rat(24414) glutamate receptor, metabotropic 1
- domestic guinea pig(100730891) glutamate receptor, metabotropic 1
- naked mole-rat(101712477) glutamate receptor, metabotropic 1
- Domestic Rabbit(100356201) glutamate receptor, metabotropic 1
- Zebrafish(100150246) glutamate receptor, metabotropic 1
- dog(484024) glutamate receptor, metabotropic 1
- domestic cat(101094104) glutamate receptor, metabotropic 1
- cow(540485) glutamate receptor, metabotropic 1
- Horse(100060603) glutamate receptor, metabotropic 1
- chicken(421614) glutamate receptor, metabotropic 1
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Small Molecule - Agonist
Small Molecule - Antagonist
Antibodies
產品編號
描述
物種活性
應用
Anti-Metabotropic Glutamate Receptor 1α Antibody, pain, CT, Chemicon®, from rabbit,
物種活性
human, monkey, rat
應用
immunohistochemistry
western blot
western blot
Anti-Metabotropic Glutamate Receptor 1 Antibody, Chemicon®, from rabbit,
物種活性
human
應用
immunohistochemistry
Anti-Glutamate Receptor 1A, Metabotropic (mGluR1A) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
feline, mouse, rat
應用
immunohistochemistry
western blot
western blot
Small Molecule - Inhibitor
Small Molecule - Mixed Agonist/Antagonist
產品編號
描述
物種
L-谷氨酸, from non-animal source, meets EP testing specifications, suitable for cell culture, 98.5-100.5%,
物種
rat, human