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Merck

CTNNB1

catenin (cadherin-associated protein), beta 1, 88kDa

同義詞:
CTNNB, MRD19, armadillo
物種:
UniProtKB ID:
基因 ID:
  • Human(1499) Summary: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009]
  • Mouse(12387) catenin (cadherin associated protein), beta 1
  • Rat(84353) catenin (cadherin associated protein), beta 1
  • naked mole-rat(101720578) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic guinea pig(100732604) catenin (cadherin-associated protein), beta 1, 88kDa
  • sheep(100294600) catenin (cadherin-associated protein), beta 1, 88kDa
  • Domestic Rabbit(100125985) catenin (cadherin-associated protein), beta 1, 88kDa
  • Zebrafish(30265) catenin (cadherin-associated protein), beta 1
  • chicken(395964) catenin (cadherin-associated protein), beta 1, 88kDa
  • cow(539003) catenin (cadherin-associated protein), beta 1, 88kDa
  • Horse(100055241) catenin (cadherin-associated protein), beta 1, 88kDa
  • domestic cat(101097342) catenin (cadherin-associated protein), beta 1, 88kDa
  • dog(477032) catenin (cadherin-associated protein), beta 1, 88kDa

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Antibodies

產品編號
描述
物種活性
應用
单克隆抗-β-连环蛋白 小鼠抗, clone 15B8, ascites fluid,
物種活性
bovine, canine, chicken, human
應用
immunocytochemistry
immunofluorescence

immunohistochemistry

microarray

western blot
单克隆抗-β-连环蛋白, clone 15B8, purified from hybridoma cell culture,
物種活性
bovine, canine, chicken, human
應用
immunofluorescence
单克隆抗-β-连环蛋白 小鼠抗, clone 6F9, ascites fluid,
物種活性
bovine, canine, chicken, human
應用
immunofluorescence
microarray

western blot
抗-CTNNB1 (Ab-33) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
immunofluorescence
immunohistochemistry

western blot
Anti-β-Catenin Antibody, clone 2H4A7, clone 2H4A7, Upstate®, from mouse,
物種活性
human, mouse, rat
應用
immunohistochemistry
immunoprecipitation (IP)

western blot

Proteins

產品編號
描述
物種
Catenin β, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human CTNNB1,
物種
human