COMT
catechol-O-methyltransferase
同義詞:
物種:
Human COMT (1312), Mouse Comt (12846), Rat Comt (24267), fruit fly comt (47091), chicken COMT (416783), domestic cat COMT (101097022), cow COMT (618278), Horse COMT (100146509), dog COMT (445450), naked mole-rat Comt (101717730)
UniProtKB ID:
基因 ID:
- Human(1312) Summary: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]
- Mouse(12846) catechol-O-methyltransferase
- Rat(24267) catechol-O-methyltransferase
- fruit fly(47091) comatose
- chicken(416783) catechol-O-methyltransferase
- domestic cat(101097022) catechol-O-methyltransferase
- cow(618278) catechol-O-methyltransferase
- Horse(100146509) catechol-O-methyltransferase
- dog(445450) catechol-O-methyltransferase
- naked mole-rat(101717730) catechol-O-methyltransferase
- domestic guinea pig(100730509) catechol-O-methyltransferase
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Antibodies
產品編號
描述
物種活性
應用
Anti-Catechol O-methyltransferase/COMT Antibody, from rabbit, purified by affinity chromatography,
物種活性
bovine, horse, human, porcine, rhesus macaque
應用
immunohistochemistry
western blot
western blot
抗-COMT 兔抗, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human, mouse, rat
應用
immunoprecipitation (IP)
western blot
western blot