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Merck

CDH1

cadherin 1, type 1, E-cadherin (epithelial)

同義詞:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
物種:
UniProtKB ID:
基因 ID:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)

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Antibodies

產品編號
描述
物種活性
應用
抗E钙粘蛋白抗体, serum, Upstate®,
物種活性
human
應用
immunohistochemistry
western blot
Anti-Pan-Cadherin antibody, Mouse monoclonal, clone CH-19, purified from hybridoma cell culture,
物種活性
psammomys (sand rat), bovine, canine, cat, chicken, ferret, frog, guinea pig, hamster, human, monkey, mouse, rabbit, rat, snake
應用
immunofluorescence
immunohistochemistry

western blot
抗-CDH1 兔抗, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
immunohistochemistry
Monoclonal Anti-Uvomorulin/E-Cadherin antibody produced in rat, clone DECMA-1, purified from hybridoma cell culture,
物種活性
dog, mouse
應用
immunofluorescence
immunoprecipitation (IP)

western blot
抗 E-钙黏蛋白 兔抗, affinity isolated antibody,
物種活性
human
應用
ELISA
immunofluorescence

immunohistochemistry

western blot

Proteins

產品編號
描述
物種
E-钙粘素 人, recombinant, expressed in E. coli, 0.5 mg protein/mL,
物種
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
物種
mouse